VASCULAR THROBOSIS PREVENTION IN ARTERY SURGERY P. Niedziela J. Michalak W. Kobusiewicz,P. Niedziela J. Michalak W. Kobusiewicz, Department of Vascular Surgery Medical Academy, Lublin, Poland PRAGUE 2002

thrombosis in case obesity age above 40 malignant cancers hormonal drug varicose veins

< 1 hours 57 % 1 – 3 hours 35 % > 3 hours 8 %

methods physicalpharmacological

Standard heparin Standard heparin LMWH LMWH Dextran Dextran Oral anticoagulants Oral anticoagulants Acetylsalicylic acid Acetylsalicylic acid

low risk low risk medium risk medium risk high risk high risk

age up 40 have undergone operative treatments without clinical risk factors

more than 40 years old major arterial treatments without clinical risk factors

above 40 years old vast reconstructive operations with additional risk factors

Prophylaxis of deep vein thrombosis standard heparin standard heparin low molecular weight heparin low molecular weight heparin

Fraxiparin0,01ml/kg Clexane 1 mg/ kg Clivarin jm/kg

fewer complications fewer complications lower cost of treatment lower cost of treatment convenient way of administration convenient way of administration