CELL PHYSIOLOGY CELLS ARE THE BASIC UNIT OF LIFE
CELL ORGANELLES MitochondrionNucleus
CELL ORGANELLES n Cell Membrane n Nucleus n Endoplasmic reticulum n Golgi complex n Mitochondria n Lysosomes n Microfilaments and microtubules n Vesicles
THE NUCLEUS n Site of DNA (In chromosomes) n Enclosed by a membrane
DNA REPLICATION n The double helix “unzips” n New bases pair up with the old ones n The molecule replicates itself n Two identical copies each with one old strand and one new
RNA TRANSCRIPTION n Messenger RNA “copies” from DNA n m-RNA caries the message to the rough ER
ENDOPLASMIC RETICULUM n Fluid filled membrane system n Rough ER: Protein Synthesis n Smooth ER: Synthesis of Lipids
Rough ER : Site of Protein Synthesis n Rough ER contains ribosomes n M-RNA attaches to ribosome n A triplet of bases is a Codon n Transfer RNA has an anticodon at one end and the appropriate amino acid at the other n As the code is read, amino acids are assembled into a protein
ER -> Golgi -> Secretion
Exocytosis n Vesicles fuse with the membrane n They open to the outside and discharge their contents
MITOCHONDRIA n Extract Energy from Food Fuels n Energy is stored in ATP n Aerobic Metabolism
Anaerobic Metabolism n Sugar can be burned without oxygen - anaerobically n Far more energy released from burning sugar aerobically n Glycolysis is anaerobic-carried out in cytosol n Glucose ----> 3 Carbon fragments plus 2 ATP
Aerobic Metabolism n Pyruvic Acid (3 C fragment) enters Mitochondria n Combines with Coenzyme A loosing a CO 2 and becoming Acetyl Coenzyme A (2 C fragment) n This fragment enters a cyclic reaction scheme, the Citric Acid Cycle n Ultimately, 34 more ATP’s are produced
THE CYTOSKELETON n Microtubules n Microfilaments n Intermediate Filaments n Microtubular Lattice