LINCS LINCS Meeting Goals and Expected Outcomes of LINCS Consortium Jennie Larkin.

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Presentation transcript:

LINCS LINCS Meeting Goals and Expected Outcomes of LINCS Consortium Jennie Larkin

LINCS LINCS Meeting Goals LINCS Phase 1 Activities 1.Large-scale production of perturbation-induced molecular and cellular signatures 2.Creation of a database, common data standards and public user interface for accessing the data 3.Computational tool development and integrative data analyses 4.Development of new cost-effective, molecular and cellular phenotypic assays 5.Integration of existing datasets into LINCS

LINCS LINCS Meeting Goals Establish the LINCS consortium Learn other’s research Identify joint areas of interest Establish a joint project with one or more groups Identify common LINCS challenges How to integrate multi-dimensional assays into a single coherent LINCS database? How to mine and analyze LINCS data? How to encompass more biomedical research areas into LINCS? How to leverage other activities?

LINCS LINCS Meeting Goals Establish the LINCS consortium Learn other’s research Identify joint areas of interest Establish a joint project with one or more groups Identify common LINCS challenges How to integrate multi-dimensional assays into a single coherent LINCS database? How to mine and analyze LINCS data? How to encompass more biomedical research areas into LINCS? How to leverage other activities?

LINCS LINCS

LINCS LINCS consortium members Broad U54 HMS U54 Miller- Jensen U01 Califano U01 Jaffe U01 Meldrum U01 Mootha & Bao Medvedovic U01 Schurer U01 Zhou U01 Snyder

LINCS LINCS identifying initial groups Broad U54 HMS U54 Miller- Jensen U01 Califano U01 Jaffe U01 Meldrum U01 Mootha & Bao Medvedovic U01 Schurer U01 Zhou U01 Snyder

LINCS LINCS building the consortium Broad U54 HMS U54 Miller- Jensen U01 Califano U01 Jaffe U01 Meldrum U01 Mootha & Bao Medvedovic U01 Schurer U01 Zhou U01 Snyder

LINCS LINCS building the consortium Broad U54 HMS U54 Miller- Jensen U01 Califano U01 Jaffe U01 Meldrum U01 Mootha & Bao Medvedovic U01 Schurer U01 Zhou U01 Snyder Identify common interests Identify key collaborations Join/form working groups WG

LINCS LINCS Meeting Goals What can we do in the next 2 years to make LINCS succeed?