Molecular and Biomedical Sciences at the University of Nebraska-Lincoln.

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Presentation transcript:

Molecular and Biomedical Sciences at the University of Nebraska-Lincoln

Areas of Strength at UNL Microbiology Virology Bacteriology Redox Biology Biochemistry Vet Biomedicine

MICROBIOLOGY at UNL HIV HSV EBV KSHV VSV PRRSV HPV Bacteria Fungi

Nebraska Center for Virology 40 Members on 3 campuses UNL

Funded by Grant P20RR15635 from the COBRE of the National Center for Research Resources $10,950,000/ 5yrs ( ) Extramural Funding by NCV members since year 2000 Over 39 million (PHS funding) since incept. NIH Graduate Student and Postdoc Training Grant T32 - Training grant in Virology (UNL) Fogarty International Training Grant $2, 100,000

New Virology Building Groundbreaking October 4th, 2006 Ken Morrison Research Building

What’s Going on in the Beadle Center?

In the Beadle Center Biology Nebraska Center for Virology Biochemistry Center for Redox Biology Plant Science Biotech Center

Dr. James Alfano Dr. Marjorie Lou Dr. Ruma Banerjee Dr. Stephen Ragsdale Dr. Joseph Barycki Dr. Ashraf Raza Dr. Donald Becker Dr. George Rozanski Dr. Liang-cheng Du Dr. Harold Schultz Dr. Howard Gendelman Dr. Greg Somerville Dr. Vadim Gladyshev Dr. Julie Stone Dr. Jonathan Kipnis Dr. Mark Thomas Dr. Jaekwon Lee Dr. Mark Wilson Dr. Ming-Fong Lin

Microscopy Core Facility Dr. Joe Zhou, Director microscopy imaging systems technical support in bio-imaging state-of-the-art equipment three new electron microscopes a BioRad MRC1024ES confocal laser scanning microscope two advanced fluorescence microscopes with video

Biosafety Level 3 Facilities Live HIV and other virus studies East Campus Soon to be commissioned Beadle Center Ken Morrison Building Future

Flow Cytometry Danielle Shea Director: Dr. Charles Kuszynski Beadle East Campus 2 Locations: Facscalibur Bead-Array

UNL Genomics Facility Gene-chips DNA Sequencing Hybridization

Structural/Protein Core UNL Department of Chemistry Director: Dr. Ronald Cerny Exact Mass Measurement – Electron Ionization MS Low Resolution Fast Atom Bombardment (FAB) MS Exact Mass Measurement – FAB MS Direct Injection (single component) Electrospray Ionization (ESI) Liquid Chromatography – Mass Spectrometry (LC/MS) Matrix Assisted Laser Desorption Ionization MS (MALDI) Peptide Chrystallography Core H. Moriyama

VBMS Biomedical Sciences (Animals and Humans) Epidemiology Bacteriology Virology Cell Biology Parasitology Toxicology Barletta, Raul Duhamel, Gerald E., Jones, Clinton J. Lou, Marjorie F. Moxley, Rodney A. Osorio, Fernando A. Pattnaik, Asit K., Somerville, Greg, Herpesvirus PRRSV Bacterial Path

Etsuko Moriyama Steve Ladunga Computer Science Mike Fromm

Pesticide Absorption into the Body Fuzzy Modeling of Skin Permeability Coefficients Transdermal Delivery of Antisense Oligonucleotides Biosignals & Systems Medical Imaging Biomedical imaging Noninvasive blood flow velocity measurement Single molecule imaging and tracking DNA sequencing instrumentation

The Future at UNL? Areas of Collaboration? Cross-field: Nanotechnology and molecular biology, Computer modelling; complex systems Microbiology of pathogens, drug and vaccine development (Strong Chemistry and Animal Sciences). Multidisciplinary Cross-department, Cross-campus Collaborations. More Growth in Funding (despite recent NIH budget dips). Unique Niches.