Luke Mitcheson Clinical Psychologist Contingency Management Advanced Clinical Management of Addiction Module Luke Mitcheson Clinical Psychologist

Objectives Understand what CM is and aims to achieve Understand the evidence base Consider implementation issues

Introduction to Contingency Management What is Contingency Management? How has it been used in General Health Care?  How has it been delivered in drug misuse? BBV Methadone Maintenance What is the evidence for effectiveness? CM in drug use (data from NICE) What NICE had to say Delivering CM in practice

Theory

What is Contingency Management? Conditioning in which an operant (voluntary) response is brought under stimulus control by virtue of presenting reinforcement contingent upon the occurrence of the operant response OR The basic process by which an individual's behaviour is shaped by reinforcement or by punishment Based on operant conditioning principles (Skinner)

Application of operant conditioning Add Subtract Positive Positive reinforcement increases behaviour Extinction decreases behaviour Negative Punishment Negative reinforcement Increases behaviour

Add Subtract Positive Negative Extinction – ceasing any type of reinforcer weakens behavioural response Add Subtract Positive Give voucher for drug free UDS Stop giving praise for drug free UDS Negative Yell at client for drug free UDS Lift daily supervised consumption for drug free UDSs

The Essential Elements A discrete behaviour under voluntary control Quantifiable targets – e.g. child does 15 minutes piano practice Identified reinforcement (incentives, rewards) - e.g. praise, vouchers, prizes, privileges, cash Clear contingent relationship between behaviour and reinforcement (schedules of reinforcement which are  consistent and immediate(at least initially) ) All reinforcement takes place in a context of already existing contingencies (AB-C)

Evidence

Use in General Health Care Children – Star Charts (NICE – Nocturnal Enuresis) Attendance for mammograms, cervical smears, TB screening/treatment (Giuffrida & Torgenson, 1997, BMJ) Challenging behaviour in learning difficulties (Howlin et al 2009) Depression (Martel et al, 2004) The Quality and Outcomes Framework for primary care (Lester and Rowland, 2007) Attendance at the gym (Charness & Gneezy 2009) Smoking cessation (Volpp et al 2009) Medication compliance (Claassen et al 2007)

NICE view of CM An effective and cost-effective intervention for improving treatment outcomes for problem drug users (NICE, 2007) The only recommended intervention for stimulant drug users

CM in Drug Misuse Adherence to healthcare interventions – e.g. Hep B vaccinations Stimulants – abstinence Methadone – reduce illicit opiate/stimulant ‘use-on-top’ Detoxification – improved adherence

Adherence to Physical Health Interventions 2 x rate for TB test/Hep B vaccination, with £5-10 reward Threefold for 6-month return rate (Seal et al, 2003)

Methadone Maintenance- CM for Illicit Drug Use Most substantial evidence base Large and consistent effect Participants shown to remain abstinent for as long as 6 months Cost effective QALY health care costs alone = £15,000 QALY including criminal justice = £74 Forest plot on next slide relates to this slide

Contingency Management and MMT

CM for Opiate Detoxification More likely to detox successfully More likely to achieve abstinence

How ethical do you think it is to use offer service users vouchers ? Discussion How ethical do you think it is to use offer service users vouchers ?

So why isn’t CM routinely used? In a survey of all NHS drug clinics for opiate users in England, NO SERVICE was identified as providing a structured CM programme (Weaver et al, 2007)

Concerns…. The acceptability and perceptions of CM to the general public and service users, the attitudes of staff and senior managers. In particular, these concerns include: The intervention may ‘reward’ illicit drug use The effects will not be maintained long-term The system is open to abuse as drug users may ‘cheat’ their drug tests

The unusual circumstances required to conduct RCTs and non-representativness of participants (exclusion criteria) The costs associated with its implementation Staff are not trained: major training programme required to implement Cultural difference between US health care system and publicly funded English system Incentive-based systems will not work outside the healthcare system (USA) in which they were developed Differences in the welfare benefits systems between the USA and England (will UK users lose benefits?)

Implementation

Key issues in implementing a CM programme (Petry, 2006) Robust, routine testing for drug misuse Targets agreed in collaboration with service users Incentives provided in a timely and consistent manner Relationship between treatment goal and incentive schedule understood by service users Incentives that are perceived to be reinforcing and support a drug-free lifestyle

5 key aspects of implementing CM (Kellogg et al, 2005) Rewards should be given frequently Should be easy to earn rewards at the start Rewards to include material goods and services that are of use and value to service users Connection between reward and behaviour clear Increased emphasis on reward-oriented not punishment-oriented approaches

Frequency and ease of earning rewards at the start Closely linked Frequent rewards = stronger connection to behaviour Target behaviour must not be too difficult: ‘successive approximation’ (e.g. Elk et al, 1995)

Material goods and services Rewards should be genuinely rewarding for service user For example, vouchers and clinic privileges should all be chosen in conjunction with service user

Connection between reward and behaviour Rewards are more effective if their distribution is directly connected to specific and observable behaviours The greater the delay in receiving the reinforcement, the weaker its effect

Reward-oriented rather than punishment-oriented Almost all trials showing efficacy of CM have been reward-oriented (e.g. Higgins et al, 1993; Stitzer et al, 1992) Adding a punitive aspect to a CM reward-oriented treatment has not found to be effective (Iguchi et al, 1988)

Maintenance of behaviour after reinforcement Don’t terminate a CM programme until target behaviour is stabilised Reduce frequency and value of rewards towards end of programme (e.g. Higgins 1993, 1994; Petry 2004,2005)

Implementing CM in the NHS Major studies of implementation in services where initially there was considerable resistance Positive shifts in staff attitudes (McGovern et al, 2004; Kellogg et al, 2005; Kirby et al, 2006; Ritter and Cameron, 2006)

Endorsement of the programme by senior management and clinicians Provision of a comprehensive education and training programme Recognition by staff that CM is an intervention aimed at changing behaviours not simply reinforcing people for generally good behaviour Shift in focus of service to one that is reward orientated Kellogg et al (2005)

Factors to be considered when developing an programme in the NHS Integration of CM with key working responsibilities of staff Identification of groups of drug users who are most likely to benefit Development of near patient testing Impact of service users benefits

Reinforcement schedules Clinic privileges (Stitzer et al, 1992; 1986) Voucher reinforcement (Petry et al, 2000) Cash (Malotte et al, 1998; Seal et al, 2003) Prizes (Petry et al, 2005; Prendegast et al, 2006)

3. Book first appointment with named worker Incentivised attendance and completion of care plan programme for primary crack users TRIAGE Appt 1 Appt 2 Appt 3 Appt 4 TRIAGE 1. Ensure eligibility 2. Explain programme 3. Book first appointment with named worker 1. Work on full assessment and care-plan 2. Give £10 voucher 3. Explain reward schedule for session 2 and 3 1. Work on full assessment and care-plan 2. Give £10 voucher 3. Explain reward schedule for session 2 and 3 1. Work on full assessment and care-plan 2. Give £10 voucher 3. Give £10 bonus as per protocol Treatment as usual Eligibility Criteria: Primary crack users Not in treatment in past 12 weeks Not in receipt of / seeking an opiate substitute prescription Not having participated in this programme for I year

The Harbour Steps

Lambeth voucher-CM 24 tests on Monday, Wednesday & Friday Escalating schedule starting at £1 Up by £0.5 for each successive –ive test Bonus for each series of 6 –ive tests Re-set following +ive test or DNA Return to previous level for 6 –ives (if time) £40 bonus if client attends all 24 sessions Total voucher value possible = £282 Harbour voucher credits recorded in account book and withdrawn on treatment days

References Higgins ST, Budney AJ, Bickel WK, Foerg FE, Donham R, Badger GJ. Incentives improve outcome in outpatient behavioral treatment of cocaine dependence. Arch Gen Psychiatry 1994; 51: 568-76. Lussier JP, Heil SH, Mongeon JA, Badger GJ, Higgins ST. A meta-analysis of voucher-based reinforcement therapy for substance use disorders. Addiction 2006; 101:192-203.  Petry NM, Peirce JM, Stitzer ML, Blaine J, Roll JM, Cohen A, et al. Effect of prize-based incentives on outcomes in stimulant abusers in outpatient psychosocial treatment programs: A national drug abuse treatment clinical trials network study. Arch Gen Psychiatry 2005. ; 62:1148-56 Peirce JM, Petry NM, Stitzer ML, Blaine J, Kellogg S, Satterfield F, et al. Effects of lower-cost incentives on stimulant abstinence in methadone maintenance treatment: a National Drug Abuse Treatment Clinical Trials Network study. Arch Gen Psychiatry 2006. ; 63:201-8. Kellogg SH, Burns M, Coleman P, Stitzer M, Wale JB, Kreek MJ. Something of value: the introduction of contingency management interventions into the New York City Health and Hospital Addiction Treatment Service. J Subst Abuse Treat 2005; 28: 57-65 Petry NM, Alessi SM, Hanson T, Sierra S. Randomized trial of contingent prizes versus vouchers in cocaine-using methadone patients. J Consult Clin Psychol 2007; 75: 983-91 Olmstead TA, Petry NM. The cost-effectiveness of prize-based and voucher-based contingency management in a population of cocaine- or opioid-dependent outpatients. Drug Alcohol Depend 2009. ; 102:108-15.