Opener: What controls all cell activities and determines our features?

Alfred Hershey and Martha Chase’s experiment Section 12-1 Bacteriophage with phosphorus-32 in DNA Phage infects bacterium Radioactivity inside bacterium Bacteriophage with sulfur-35 in protein coat Phage infects bacterium No radioactivity inside bacterium Go to Section:

Hershey-Chase Experiment Section 12-1 Bacteriophage with phosphorus-32 in DNA Phage infects bacterium Radioactivity inside bacterium Bacteriophage with sulfur-35 in protein coat Phage infects bacterium No radioactivity inside bacterium Go to Section:

Hershey-Chase Experiment Section 12-1 Bacteriophage with phosphorus-32 in DNA Phage infects bacterium Radioactivity inside bacterium Bacteriophage with sulfur-35 in protein coat Phage infects bacterium No radioactivity inside bacterium Go to Section:

Rosalyn Franklin Her work was used by James Watson and Francis Crick to figure out the structure of DNA

Percentage of Bases in Four Organisms Section 12-1 Percentage of Bases in Four Organisms Source of DNA A T G C Streptococcus 29.8 31.6 20.5 18.0 Yeast 31.3 32.9 18.7 17.1 Herring 27.8 27.5 22.2 22.6 Human 30.9 29.4 19.9 19.8 Chargaff’s Rule! Go to Section:

James Watson and Francis Crick

DNA Nucleotides Purines Pyrimidines Section 12-1 Phosphate group Adenine Guanine Cytosine Thymine Phosphate group Deoxyribose Go to Section:

Structure of DNA Nucleotide Hydrogen bonds Sugar-phosphate backbone Section 12-1 Nucleotide Hydrogen bonds Sugar-phosphate backbone Key Adenine (A) Thymine (T) Cytosine (C) Guanine (G) Go to Section:

DNA Replication Section 12-2 Go to Section: Original strand DNA polymerase New strand Growth DNA polymerase Growth Replication fork Replication fork Nitrogenous bases New strand Original strand Go to Section:

THE DNA SONG!! To the tune of “Row, row your boat” We love DNA Made of nucleotides. Sugar, phosphate and a base Bonded down one side. Adenine and thymine Make a lovely pair. Cytosine without guanine Would feel very bare.