Perinatal Pathology: A Review Dr G Mortimer UCHGalway

Totals 2003 Mothers: 1,203P 1,941M = 3,144 Mothers: 1,203P 1,941M = 3,144 Babies: 1,223P 1,976M = 3,199 Babies: 1,223P 1,976M = 3,199 Singletons: 1,183P 1,907M = 3,090 Singletons: 1,183P 1,907M = 3,090 Twins: 20P 33M = 53 Twins: 20P 33M = 53 Triplets: 0P 1M = 1 Triplets: 0P 1M = 1

Total Babies 1999: 2, : 2, : 2, : 2, : 3, : 3, : 3, : 3, : 3, : 3,199

Multiple Births 1999: Twins 48, Triplets 6; Total = : Twins 48, Triplets 6; Total = : Twins 45, Triplets 0; Total = : Twins 45, Triplets 0; Total = : Twins 42, Triplets 1; Total = : Twins 42, Triplets 1; Total = : Twins 56, Triplets 4; Total = : Twins 56, Triplets 4; Total = : Twins 53, Triplets 1; Total = : Twins 53, Triplets 1; Total = : Twins 61, Triplets 0; Total = : Twins 61, Triplets 0; Total = 61

Non-National Deliveries 1999: % 1999: % 2000: % 2000: % 2001: % 2001: % 2002: % 2002: % 2003: % 2003: %

Perinatal Mortality Rates Stillbirths 0.5% 0.8% 0.7% 0.5% 0.7% Stillbirths 0.5% 0.8% 0.7% 0.5% 0.7% NND 0.4% 0.3% 0.2% 0.4% 0.3% NND 0.4% 0.3% 0.2% 0.4% 0.3% Total Rate 0.9% 1.1% 0.9% 0.9% 1.0% Total Rate 0.9% 1.1% 0.9% 0.9% 1.0%

Perinatal Loss 2003 Total = 31 Total = Antepartum Stillbirths 21 Antepartum Stillbirths 10 Neonatal Deaths 10 Neonatal Deaths

Perinatal Deaths Autopsy No Autopsy Autopsy No Autopsy All: (55%) 14 (45%) All: (55%) 14 (45%) NND: 10 3 (30%) 7 (70%) NND: 10 3 (30%) 7 (70%) SB: (66%) 7 (33%) SB: (66%) 7 (33%)

Perinatal Deaths 2003 Stillbirths: 9P 12M = 21 (0.7%) Stillbirths: 9P 12M = 21 (0.7%) Early NND: 6P 4M = 10 (0.3%) Early NND: 6P 4M = 10 (0.3%) Total: 15P 16M = 31 (1.0%) Total: 15P 16M = 31 (1.0%)

Causes Antepartum Deaths Prims Multips Total Prims Multips Total Unexplained Abruptio TTS Cord Accident IUGR Malformation 1 0 1

Stillbirths UCHG Congenital anomalies Congenital anomalies Asphyxia Asphyxia PET 41 5 PET 41 5 Maternal disease 25 7 Maternal disease 25 7 IUGR IUGR Unexplained Unexplained Other 30 4 Other 30 4 Total Total

Stillbirth Rate/1000 UCHG Congenital anomalies Congenital anomalies Asphyxia Asphyxia PET PET Maternal disease Maternal disease IUGR IUGR Unexplained Unexplained Other Other Total Total

Causes Neonatal Deaths Prims Multips Total Prims Multips Total Malformations Malformations Prematurity Prematurity Infection Infection TTS TTS Abruptio Abruptio 1 0 1

Autopsies 2004 Total : 14 Total : 14 Neonates : 5 Neonates : 5 Stillbirths : 9 Stillbirths : 9

Neonatal Autopsies 2004 Twins TTS MoDi Early Twins TTS MoDi Early T2 Premature DiDi/Infarct Early T2 Premature DiDi/Infarct Early RDS Late RDS Late Congenital Anomaly Early Congenital Anomaly Early

Stillbirth Autopsies 2004 Unexplained 7 Unexplained 7 Congenital Anomaly 2 Congenital Anomaly 2

Unexplained Stillbirths 2004 (8) Twins TTS MoDi Infarction Twins TTS MoDi Infarction T1 DiDi Infarction T1 DiDi Infarction Acute chorioamnionitis + Infarction Acute chorioamnionitis + Infarction Acute chorioamnionitis + SROM Acute chorioamnionitis + SROM Infarct + PET-type maternal vasculopathy Infarct + PET-type maternal vasculopathy

Sudden Infant Death Syndrome Cases 2 Cases