20,000 GENES IN HUMAN GENOME; WHAT WOULD HAPPEN IF ALL THESE GENES WERE EXPRESSED IN EVERY CELL IN YOUR BODY? WHAT WOULD HAPPEN IF THEY WERE EXPRESSED IN THE WRONG CELLS? WARM-UP # 5 1/13/2015
Why is control of gene expression important? Antennapedia
How do cells know which genes to use? 98% of human genome does NOT code for proteins! RNA polymerase – enzyme that produces mRNA
Promoter Region of DNA that begins transcription
TRANSCRIPTION FACTORS o Proteins that control transcription o Bind to enhancer DNA o Always present in cell, but most likely have to be activated before they will bind to DNA
Transcription Factors Essential for the transcription of all protein- coding genes Can either repress or enhance transcription