Automated Immunoassays Multi-test immunoassays are the most widely used rapid test format – worldwide – ELISA / EIA (Assurance EIA, TECRA) – ELFA (Vidas) Benefits –Low cost/test –Low labor cost with automation –Capable of high throughput –Validated, proven technology

 Full automation of EIA procedure  Sample dispensing  Reagent delivery  Washing  Incubation  Photometric reading  Results interpretation BioControl EIA Automation

 Continuous Loading  Bi-directional LIMS Compatibility  High Throughput  Up to 186 samples and controls per run  Continuous loading  Highly adaptable open platform Pre-programmed for TRANSIA ® PLATE Pre-programmed for Assurance EIA ® Compatible with all EIA assays BioControl EIA Automation Options

BioControl EIA’s Final Enrichment Transfer 1 mL to Cluster tubes Inactivation heating block Load tubes and Reagent On Gemini Vidas Final Enrichment Transfer 0.5 mL to Vidas Test Strip Inactivation Heating Block Load Test Strips and SPRs on Vidas Comparable Hands-On Time

Comparison of Through-put Throughput of 1 Gemini = 3 Vidas Systems GeminiVidas 8 h480 samples samples 24 h1600 samples samples

Gemini vs Vidas CapabilityGeminiVidasWinner Max Capacity288 samples / controls 30 samples / controls Gemini Continuous LoadingYesNoGemini Multiple Assays per RunYesYes – limited by capacity Gemini Hands-on TimeMinimized by high sample capacity Increased by low sample capacity Gemini Individual Run TimeApprox 2 hrApprox 1 hrVidas Overall Run TimeMinimized by high sample capacity Increased by low sample capacity Gemini Calibration1 / year28 / yearGemini Barcode ReaderYes Equivalent LIMS CapabilityYes Equivalent

Automates each and every step WASH Washer 8 channels Aspirate / dispense needles 3 wash buffers Customized wash patterns PIPET Pipettor Disposable tips Capacitive liquid level detection Pipetting pressure monitoring 300 µL tips ( µL) – Samples 1100 µL tips ( µL) - Reagents

Automates each and every step INCUBATE 2 incubator chambers Independently controlled Shaking capacity Temperatures up to 45°C 3 ambient temperature positions Unique modular design Easy service & Maintenance Minimizes down time Reduces repair costs READ Absorbance reader nm wavelength Single or dual wavelength Range 0.0 – 3.0 OD

On-board Computer Computer Ports 3 USB ports for external peripheral keyboard, mouse, printer, etc… VGA monitor port LAN cable connection PS2 port Touch-Screen Interface Full function user interface Automates each and every step and MORE!

Multiple Assays Same plate –common protocol Different plates – common protocol or different protocols Continuous loading of resources Plates and tips Samples, and reagents Instrument will show when Plate 3 can be loaded Continuous operation Initiate new assays during run Flexible to meet your high throughput needs

Accepts individual sample tubes or cluster tubes 12 loading bay lanes Accepts both sample and reagent racks Accepts reagent bottles directly from kit No reagent transfer

Automated resource tracking Reagent volume tracking Disposable tip tracking Resource verification Are reagents present Sufficient reagent volume Sufficient tips Automatic schedule optimization Multiple plates / assays Addition of new samples/ assays

Assurance EIA Pathogen Tests

TRANSIA ® PLATE Salmonella Gold TRANSIA ® PLATE Listeria TRANSIA ® PLATE Listeria monocytogenes TRANSIA ® PLATE Staphylococcal Enterotoxins TRANSIA PLATE EIA Pathogen Tests *TRANSIA ® is also available for Allergen and Chemical Residue detection