Kelsie Thu 1, Daiana Becker 1, Raj Chari 2, Wei Zhang 3, Calum MacAulay 1, Adi Gazdar 3, Stephen Lam 1, Wan Lam 1 1 BC Cancer Research Centre, Vancouver,

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Kelsie Thu 1, Daiana Becker 1, Raj Chari 2, Wei Zhang 3, Calum MacAulay 1, Adi Gazdar 3, Stephen Lam 1, Wan Lam 1 1 BC Cancer Research Centre, Vancouver, Canada, 2 Harvard Medical School, Boston, USA, 3 University of Texas Southwestern, Dallas, USA World Conference on Lung Cancer, Amsterdam 2011 July 4th, 2011

 7 th leading cause of cancer death in world Sun S. et al. Nat Rev Cancer 7(10): (2007)

Copy number profiles generated from Affymetrix SNP 6 arrays

MSKCCdbGaP p = BCCRC p = 0.004p = 0.128

IL12B, RNF145, UBLCP1 MAT2B C7orf10, INHBA ABCA13 A2BP1, ABAT, C16orf68, CARHSP1, PMM2, TMEM186  6 minimal common regions of copy number gain specific to NS  5q  7p  16p