Capsules for Drug Delivery Stepwise Adsorption of Polyelectrolyte Molecules on Dissolvable Templates Final Product: The Polyeelctrolyte Capsule Removal.

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Presentation transcript:

Capsules for Drug Delivery

Stepwise Adsorption of Polyelectrolyte Molecules on Dissolvable Templates Final Product: The Polyeelctrolyte Capsule Removal of the Core Fabrication of Polyelectrolytes on Soluble Templates

a b cd ef g h Core Removal

Empty Capsules Exclude Polymers

Monodisperse Capsules Obtained on Melamin Templates

Scanning Electron Microscopy of Capsules - Big and Small

10 m   

Threeedimensional Replicas of Cells - The Echinocyte The Replica – a Polyelectrolyte Capsule The Template

10 m  10 min 1h 4h Adjusting the Permeability by Charging the Wall Permeation of Fluorescein through highly charged walls

Filled Capsules Crystals everywhere Only in Capsules

The Building Blocks PAH PSS

Enzyme Encapsulation by Changing the Wall Permeability 5 m   A FITC-Labelled Protein is encapsulated

Osmotic Swelling And Shrinking Layer Mechanics Tailored Polymers for Adsorption und Nucleation Catalysis on Nanopartiicles or Polymeric Catalysts Optical sensors for pH Labelled polymers or Copolymers Microreactors Microsensors Micromechanics Mikrocarriers

(a)(b) (c) Capsules with Remains

Capsules filled by Synthesis of Polymers inside

5 µm Writing on Capsules Reduction of Silver Ions on the Capsule Surface by Laser /

Scanning Force Microscopy – The Texture

Capsules with Oil inside

Coated Colloids – Surface Engineering

Reversibel Osmotic Swelling and Shrinking

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