Public Health Impact Basic Science Discovery Translational Research Continuum Proposed Human Application Proven Clinical Application (clinical trials)

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Public Health Impact Basic Science Discovery Translational Research Continuum Proposed Human Application Proven Clinical Application (clinical trials) Clinical Practice (effectiveness or outcomes research) T1 Lab to clinical T2 Safety/efficacy T3 Implementation & adoption Dissemination Adapted from: Woolf, The meaning of translational research and why it matters, JAMA, 2008 Drolet & Lorenzi. Translational research: understanding the continuum…, Translational Research, 2011.

SEC Obesity Prevention Symposium Obesity Prevention Genetic Influences Physiology Early Life Influences Environmental Influences Interventions Family, School, Community & Workplace Technology Community Actions Policy *Ya-Ziong Tao (Anatomy, Physiology, Pharmacology *Danielle Wadsworth (Kineseology) *Bonnie Sanderson; *Ann Lambert (Nursing) *Jan Kavookjian (Pharmacy) * AU presenters

Does this resemble a “Cluster” in Translational Research? Health Concern Genetic Influences Physiology Human Influences Environment Influences Interventions Community Actions Health Policy T1 Lab to clinical T2 Safety/effic acy T3 Implementation & adoption Dissemination

School of Nursing- Research Focus Translational (“T-3”) & dissemination with multidisciplinary collaboration Obesity prevention Diabetes – self management skills CVD- prevention thru management; Elderly & chronic disease – caregiving Pet-assisted therapy Military – wounded warrior Simulation Health disparity and underserved populations

Nursing Research Opportunities Build on current strengths: Outcomes Research - “Big data” Intervention research ◦Health disparities ◦CVD and risk factors - prevention and disease management Expand potential abilities: “T1 and T2” collaborations ◦Nursing physiologist; genetics ◦Nursing informatics ◦Biostatistician

Current priority research initiatives: End-of-Life and Palliative Care Symptom - Pain ◦Biology of pain ◦Assessment and management of pain Examples funding agencies applicable for nursing: NIH – R-15; R-21 AHRQ; PCORI HRSA AHA; ADA; CDC

What or who is needed? AU – Strategic Focus in Cluster Hire in Health Science Prioritize health concern ◦Public Health and Alabama need ◦Align with funding opportunities Consider full spectrum of Translational Research ◦Identify and “harness” the current AU talent and expertise ◦Identify the gaps for target hires within the translational continuum