This article and any supplementary material should be cited as follows: Nitz JC, Perrier J, Cook P. In-vivo trial results of a novel ultrasonic cough stimulator.

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This article and any supplementary material should be cited as follows: Nitz JC, Perrier J, Cook P. In-vivo trial results of a novel ultrasonic cough stimulator. J Rehabil Res Dev. 2012;49(9):1421–30. Slideshow Project DOI: /JRRD JSP In-vivo trial results of a novel ultrasonic cough stimulator Jennifer C. Nitz, PhD, MPhty, BPhty; John Perrier, BPhty; Peter Cook, MBBS, FANZCA, FCICM

This article and any supplementary material should be cited as follows: Nitz JC, Perrier J, Cook P. In-vivo trial results of a novel ultrasonic cough stimulator. J Rehabil Res Dev. 2012;49(9):1421–30. Slideshow Project DOI: /JRRD JSP Aim – Establish: Whether ultrasound (US) stimulation can safely stimulate cough. Most efficient US frequency. Whether single- or dual-sided stimulation is more effective. Relevance – Ability to cough voluntarily is absent or diminished in many clinical situations, which may predispose patients to or prolong respiratory diseases.

This article and any supplementary material should be cited as follows: Nitz JC, Perrier J, Cook P. In-vivo trial results of a novel ultrasonic cough stimulator. J Rehabil Res Dev. 2012;49(9):1421–30. Slideshow Project DOI: /JRRD JSP Method Applied stimulation with CoughStim device to 15 nondisabled and 7 unable-to-cough volunteers: – Unilaterally: 8 frequencies and 2 power levels. – Bilaterally: 2 frequencies and 3 power levels.

This article and any supplementary material should be cited as follows: Nitz JC, Perrier J, Cook P. In-vivo trial results of a novel ultrasonic cough stimulator. J Rehabil Res Dev. 2012;49(9):1421–30. Slideshow Project DOI: /JRRD JSP Results Nondisabled subjects – Cough stimulated: 80% at 0.58 MHz and 9 W unilaterally. 75% at 0.58 MHz and 6 W bilaterally Unable-to-cough subjects – Cough stimulated: 71% at 0.54 MHz and 6 W bilaterally.

This article and any supplementary material should be cited as follows: Nitz JC, Perrier J, Cook P. In-vivo trial results of a novel ultrasonic cough stimulator. J Rehabil Res Dev. 2012;49(9):1421–30. Slideshow Project DOI: /JRRD JSP Conclusion CoughStim device: – Regularly and safely produced moderately strong cough response in subjects with or without ability to cough. – Produced this effect without causing undue discomfort.