METFORMIN ZAINAB BAFFA

CONTENTS HYPOTHESIS BRIEF BACKROUND ON DIABETES MELLITUS INTRODUCTION OF THE DRUG METFORMINE CHEMICAL STRUCTURE MECHANISM SIDE EFFECTS OF METFORMINE AIMS, SOLUTIONS AND ALTERNATIVES

HYPOTHESIS Metfomin reduces the blood sugar level of people with type 2 diabetes.

TYPE 2 DIABETES

CHEMICAL STRUCTURE

MECHANISM It works in several ways; it reduces the amount of sugar made by the liver, limits the amount of sugar absorbed into the body from the diet, and makes insulin receptors more sensitive (helping the body respond better to its own insulin). All of these effects cause a decrease in blood sugar levels.

SIDE EFFECTS The most common adverse effect of metformin is gastrointestinal upset Overdose: common symptoms include vomiting, diarrhea, abdominal pain, drowsiness, and, rarely hypoglycemia or hyperglycemia. The major potentially life-threatening complication of metformin overdose is lactic acidosis, which is due to lactate accumulation. Lactic acidosis is a physiological condition characterized by low pH in body tissues and blood (acidosis) accompanied by the accumulation of lactate. The condition typically occurs when cells receive too little oxygen (hypoxia).

POSSIBLE SOLUTIONS, ALTERNATIVE Before taking metformin, be sure that you don’t have any history of heart disease, liver failure . Some of the metformin alternatives include: Lifestyle changes Other oral diabetes medications like Chlorpropamide, Glipizide. Insulin .

REFERENCES Pubmed.com Drugs.com

THANK YOU