1 © Copyright 2012 EMC Corporation. All rights reserved. MANAGING HEALTHCARE BIG DATA WITH EMC ISILON Data Storage for Medical Imaging Using EMC Isilon Scale-Out NAS February 2013

2 © Copyright 2012 EMC Corporation. All rights reserved. MANAGING HEALTHCARE BIG DATA WITH EMC ISILON Big Data in Healthcare Isilon Scale-Out NAS Healthcare Impact Summary Appendix: Isilon Technical Overview

3 © Copyright 2012 EMC Corporation. All rights reserved. Today’s Healthcare IT Challenges Massive Volume Of Patient Info Lower Efficiency Of Health IT EHR Adoption Risks Pressure From Regulatory Demands Fewer Resources Increasing Health IT Costs

4 © Copyright 2012 EMC Corporation. All rights reserved. The Case for Big Data in Healthcare Healthcare IT executives cite the soaring costs and complexities associated with digital medical image storage as one of the most significant challenges they face. Medical image archives are increasing by 20-40% annually and are now considered to be big data. Applications are increasingly dense with millions of slides and 3D rendering Medicare Reimbursements continue to grow in complexity

5 © Copyright 2012 EMC Corporation. All rights reserved. Source: HIMSS 2011 Leadership Survey “40% of Healthcare CIOs reported that improving the quality of patient care can mostly be achieved by improving health IT”.

6 © Copyright 2012 EMC Corporation. All rights reserved.  Overall healthcare data growth rate of 35.3% CAGR –2.9 XB to 13.5XB in 4 years with imaging growing from 0.8 XB to 3.9 XB  Accurate treatment requires more studies  More departments using medical imaging today than ever before  Image sizes are larger and more detailed  Non-structured data is growing quickly Explosive Growth in Healthcare Imaging Source: ESG Research Report 2011 – North American Health Care Provider Market Size and Forecast

7 © Copyright 2012 EMC Corporation. All rights reserved. Healthcare Storage Complexity Disparate Storage Systems for Each Department Big Data pressuring existing IT infrastructure in healthcare Departmental Picture Archiving and Communications Systems (PACS) Multitude of dedicated, differentiated storage solutions Home Directories & File Shares Document Management & PDF Generation Patient In-Processing Video & Audio Files

8 © Copyright 2012 EMC Corporation. All rights reserved. I.T. BUDGET DILEMMA Source: Forrester Research, Inc., IT Budget Allocations: Planning For 2011, December 3, 2010

9 © Copyright 2012 EMC Corporation. All rights reserved. Advance Information-enabled Decisions And Manage Health IT Big Data Problem Mitigate Health IT Risk & Compliance Reduce IT Costs & Complexity EMC Helps Healthcare Organizations…

10 © Copyright 2012 EMC Corporation. All rights reserved. “ EMC customers represent 92% of hospitals with 500+ beds” - “The 100 Most Wired U.S. Hospitals And Health Systems” “#1 Long-term storage vendor with 52% market penetration ” - U.S. HIMSS Analytics “ A top 100 healthcare IT vendor that has “excelled in your respective market segment” - Healthcare Informatics EMC Customer And Clinical Partner Depth

11 © Copyright 2012 EMC Corporation. All rights reserved. MANAGING HEALTHCARE BIG DATA WITH EMC ISILON Big Data in Healthcare Isilon Scale-Out NAS Healthcare Impact Summary

12 © Copyright 2012 EMC Corporation. All rights reserved. EMC Isilon Setting The Standard For Scale-Out NAS  Broad adoption in many markets –Corporate IT –Higher Education –Healthcare  Over 3,000 global customers –400% Y/Y Healthcare growth rate –EMC #1 NAS market (Gartner 2012)  OneFS Software –7th generation, industry-proven, innovative scale-out operating environment

13 © Copyright 2012 EMC Corporation. All rights reserved. Healthcare Customer Pain Points Separate departmental PACS storage systems require extra cycles to manage systems with different requirements Image sizes are growing for 3D Imaging, MPI and Digital Pathology, and Next Generation Sequencing Increasing number of instruments: providers purchase additional equipment annually, often with more storage for each instrument Unstructured data is a major growth factor for new diagnostic tools Records, studies, and images being stored long-term Loss of data is an expensive problem (and often results in a lawsuit) Improved treatments require more studies, which means more data

14 © Copyright 2012 EMC Corporation. All rights reserved. EMC Isilon Value Proposition for Healthcare Eliminate silos of storage Predictable scalability without added complexity Consolidate active short-term and long-term data The EMC Isilon Difference Certification with Major Alliance Players EMC Isilon certified with most major PACS vendors EMC Isilon certified with most VNAs EMC Isilon works with next wave diagnostic tools Digital Pathology, NGS, Proteomics Video Surveillance, Sleep Studies, Electron Microscopes EMC Isilon Competitive Difference “Never Migrate Again” architecture Uses standard CIFS and NFS storage protocol connections Experience the value of scale-out NAS

15 © Copyright 2012 EMC Corporation. All rights reserved. EMC Isilon: A Flexible, Single Pool of Storage for All Modalities  Simplify complexity and meet the need for scale with EMC Isilon –Consolidate data silos from each departmental PACS with a single onsite storage solution –Single file system manages from 100 TB to Petabytes –Open NAS protocols work with nearly any instrument or ISV –Easily leveraged by multiple modalities or applications –Scale performance & storage to meet any demand –Never Refresh Again: Eliminate migrations and reduce capital and operational expense

16 © Copyright 2012 EMC Corporation. All rights reserved. Isilon Scales To Any Healthcare Need  Single file system that scales from 18 TBs to over 20 Petabytes  Open NAS protocols work with any instrument or PACS provider  Scale capacity and performance within 60 seconds  Greater than 80 percent disk utilization  Massive scalability and easy to manage at any scale  Eliminate constant “Data jockeying” and migrations with OneFS Single File System  Auto-balance capacity and performance  Industry-leading data protection with +4

17 © Copyright 2012 EMC Corporation. All rights reserved. MANAGING HEALTHCARE BIG DATA WITH EMC ISILON Big Data in Healthcare Isilon Scale-Out NAS Healthcare Impact Summary

18 © Copyright 2012 EMC Corporation. All rights reserved. Keep Healthcare Data Safe EMC Isilon SmartLock policy-based retention and protection Software-based Write Once Read Many (WORM) solution  Protect Critical Healthcare Data: Keeps data immutable, protecting it from accidental or malicious alteration or deletion  Guarantee Retention: Sets minimum retention time for data with longevity requirements  Efficient & Cost Effective: Mix WORM and non-WORM data in one, general purpose system. Set retention defaults at directory and file level  Rich Functionality: Integrates seamlessly with EMC Isilon SmartPools and SyncIQ replication

19 © Copyright 2012 EMC Corporation. All rights reserved. EMC Isilon: The Bridge from PACS to VNA Defining the VNA: Vendor Neutral Archive  Enterprise-class data management system  Consolidates the individual archives associated with departmental PACS  Significant capital expenditure  Most hospitals are expected to adopt VNA in the next decade VNA  EMC Isilon is fully compliant with the requirements of the VNA  Consolidating PACS with EMC Isilon is a natural first step in the journey to VNA

20 © Copyright 2012 EMC Corporation. All rights reserved. EMC Isilon Growing Customer Momentum Healthcare and Life Sciences UCLA EMC Isilon Growing Momentum Healthcare and Life Sciences

21 © Copyright 2012 EMC Corporation. All rights reserved. Children’s Hospital Boston Critical Research Continues 24/7, 365 Days a Year—Anywhere, Anytime Challenge  Hit storage limitation with traditional SAN  Rapid and unpredictable data growth  Traditional storage cost-prohibitive and incapable of keeping pace with data growth Solution  NL Series  SyncIQ Results  Simplified data management by unifying file- based applications onto Isilon  SyncIQ® used to improve data reliability and eliminate impact of data on overall IT backup operations Applications  File based “We chose Isilon because it’s simple, cost-effective and scalable, allowing us to create an easy-to-use “bucket” of information our researchers can draw on whenever, wherever they need.” RYAN CALLAHAN Manager of Research Computing

22 © Copyright 2012 EMC Corporation. All rights reserved. St. Dominic Hospital Treats Explosive Big Data and Home Directory Growth with EMC Challenge  20 percent annual growth of Big Data  Complex multivendor environment with limited performance and scalability  Aging PACS and EMR archiving platforms running on legacy storage could no longer scale to meet growth demands Solution  NL-Series  InsightIQ, SmartLock, SnapShotIQ, SyncIQ Results  Improved image retrieval from 6 to less than 1 second  Achieved a 1,000% increase in I/O performance  Enabled unlimited scalability with no downtime  Reduced annual expenses by 50% Applications  McKesson Horizon Patient Folder (HPF)  GE Centricity PACS “We were impressed with the simplicity of EMC Isilon – especially compared to other vendor’s solutions. Having one name space for our unstructured data, medical images, home directories and document shares was very attractive and made it easier to manage. It worked right out of the box without hours of complex configuration. This was a drastic change from the other storage platforms we had purchased. ” WENDELL W. PINEGAR Applications Supervisor

23 © Copyright 2012 EMC Corporation. All rights reserved. EMC Isilon: Simple. Smart. Future-ready.  EMC Isilon scale-out NAS: –Storage solutions that move easily from departmental PACS storage to the VNA approach of tomorrow  Consolidates silos of data, for departmental storage pools –Unmatched Performance: 20x higher throughput than traditional storage –>80% disk utilization to drive cost  Scales to any healthcare need with no downtime –Massive Scalability: Scales to over 20PB –As easy to manage TB As 100TB  EMC Isilon works with next-gen technologies –Certified with PACS & VNA ISVs –Industry-leading reliability& self-healing

24 © Copyright 2012 EMC Corporation. All rights reserved. MANAGING HEALTHCARE BIG DATA WITH EMC ISILON Big Data in Healthcare Isilon Scale-Out NAS Healthcare Impact Summary

25 © Copyright 2012 EMC Corporation. All rights reserved. “Never Refresh Again” Architecture Meet Your Big Data Healthcare Requirements with EMC Isilon One File System, One Volume Storage Management Simplicity Zero Downtime Expansion Greater than 80% utilization rates Adapt your existing storage resources Accommodate IT infrastructure changes Investment Protection: Pay As You Grow Eliminate Silos and Hot Spots

27 © Copyright 2012 EMC Corporation. All rights reserved. MANAGING HEALTHCARE BIG DATA WITH EMC ISILON Big Data in Healthcare Isilon Scale-Out NAS Healthcare Impact Summary Appendix: Isilon Technical Overview

28 © Copyright 2012 EMC Corporation. All rights reserved. EMC Isilon is the Choice, OneFS is the Reason One FS: Three layers of traditional storage architectures unified in one software layer Performance and capacity that scale linearly – from 100TB to petabytes in a single file system

29 © Copyright 2012 EMC Corporation. All rights reserved. Single Filesystem Single volume for management simplicity Single Filesystem Single volume for management simplicity 80%+ Efficiency Industry-leading raw storage utilization High Performance Over 100 GB aggregate throughput High Performance Over 100 GB aggregate throughput Easy Growth Scale in <60 Seconds with no downtime Easy Growth Scale in <60 Seconds with no downtime Multi-Tier Auto-tiering and AutoBalance Multi-Tier Auto-tiering and AutoBalance Linear Scalability Scale performance and capacity to over 20 PBs Linear Scalability Scale performance and capacity to over 20 PBs EMC Isilon Core Innovation OneFS Scale-Out Operating System

30 © Copyright 2012 EMC Corporation. All rights reserved. EMC Isilon Scale-Out NAS Architecture OneFS Operating Environment Intra-cluster Communication Layer Users or Servers Client/Application Layer Ethernet Layer Users or Servers Single FS/Volume CIFS NFS FTP HTTP HDFS for Hadoop

31 © Copyright 2012 EMC Corporation. All rights reserved. EMC Isilon Scale-Out NAS Product Family Linear Scaling of Performance & Capacity Purpose-built for IOPS- intensive, random access file-based applications A flexible solution to accelerate high- concurrent and sequential throughput applications Purpose-built for cost-effective, large capacity storage S-Series X-Series NL-Series

32 © Copyright 2012 EMC Corporation. All rights reserved. Load balancing Seamless failover Performance zones Quota management Thin provisioning High speed replication Disaster recovery Business continuance Instant recovery Data protection Isilon, Scale-Out NAS for Big Data Single File System, Single Volume Simplicity For Active, Persistent, And Archive Data WAN/LAN Primary & Nearline Storage Local/Remote Archive Client/Application Layer Virtualized Servers Clients X-series Network NL-series File immutability Protection from deletion/change NL-series Backup Accelerator S-series Automated storage tiering

33 © Copyright 2012 EMC Corporation. All rights reserved. More scalable than traditional storage systems Largest and Most Scalable File System OneFS scales from 18 TB to more than 20 PB in a single file system, single volume  Under 60 seconds to scale with no downtime  World’s fastest performance and capacity scaling  Over 100 GB/s of throughput

34 © Copyright 2012 EMC Corporation. All rights reserved. Gain New Levels of Efficiency AutoBalance automatically moves content to new storage nodes while system is online and in production Eliminates “hot spots” Enables unmatched storage capacity utilization of more than 80% AutoBalance Automated data balancing across nodes reduces costs, complexity, and risks for scaling storage AutoBalance Automated data balancing across nodes reduces costs, complexity, and risks for scaling storage EMPTY FULL BALANCED Isilon AutoBalance

35 © Copyright 2012 EMC Corporation. All rights reserved. Optimize Resources with Automated Tiering Single point of management – Single file system/single volume – Multiple performance tiers Automatic data movement – Policy-based tiering management – Transparent reallocation – NO application changes Optimize storage resources – Automatically match storage resources with data requirements – Eliminate data migration Isilon SmartPools S-Series Performance NL-Series Active archives X-Series Collaboration Reduced cost/TB Files

36 © Copyright 2012 EMC Corporation. All rights reserved. Linear, Predictable Scalability SPECsfs2008 performance test results Predictable SLAs ,800,000 1,600,000 1,400,000 1,200,000 1,000, , , , ,000 File Ops/second CIFSNFS

37 © Copyright 2012 EMC Corporation. All rights reserved. With N+2, N+3, and N+4 protection, data is 100% available if multiple drives or nodes fail With N+1 protection, d ata is 100% available even if a single drive or node fails Highly resilient, clustered architecture Unmatched Data Protection and Availability 100% FAILED And with Isilon, the more nodes in the cluster, the faster drive rebuild time

38 © Copyright 2012 EMC Corporation. All rights reserved. Enterprise Data Protection Options Isilon SyncIQ benefits – Disaster recovery – Business continuance – Disk-to-disk backup – Remote archive – Push-button simple failover/failback Block efficient, file specific Integrates with Isilon SmartLock – Policy-based retention Leverages Isilon SnapshotIQ – Per-directory policies and granularity – Unlimited snapshots per cluster – Minimal performance impact – Allows tiered snapshots SyncIQ Replication Architecture Isilon NL- Series Cluster Isilon S-Series and X-Series Cluster Fast, easy backup and recovery and disaster recovery

39© Copyright 2012 EMC Corporation. All rights reserved. Robust Enterprise Security Options  Secure Role Separation –Roles-based administration –Administration and data access separated  Secure WORM Data Protection –Isilon SmartLock –SEC 17a-4 Compliance option  Secure Isolation –Authentication Zones

40© Copyright 2012 EMC Corporation. All rights reserved. Interoperability for Operational Flexibility  Platform REST API –Simplify management and integration –Third-party application integration  VMware integration –VAAI: vStorage APIs for array integration –VASA: vSphere APIs for storage awareness –Virtual Server writeable clones  Multi-protocol support –Integrated support for industry-standard protocols –Native HDFS support

41 © Copyright 2012 EMC Corporation. All rights reserved. Industry’s First and Only Scale-Out Storage Solution With Native Hadoop Integration  Accelerate the benefits of Hadoop for the enterprise –Proven Hadoop solution, faster implementation –Greater interoperability with enterprise applications and Hadoop analytics through multi-protocol parallel access from any client  Reduce risk –Eliminates Hadoop NameNode single point of failure  Enterprise data protection –Fast snapshots, backup, and recovery –Simple, reliable data replication for disaster recovery  Ultimate flexibility –Scale compute and storage resources separately –Supports physical and virtualized server environments

February 20, 2013 Customer Presentation ISD041.3