This article and any supplementary material should be cited as follows: Foecking EM, Fargo KN, Coughlin LM, Kim JT, Marzo SJ, Jones KJ. Single session.

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Presentation transcript:

This article and any supplementary material should be cited as follows: Foecking EM, Fargo KN, Coughlin LM, Kim JT, Marzo SJ, Jones KJ. Single session of brief electrical stimulation immediately following crush injury enhances functional recovery of rat facial nerve. J Rehabil Res Dev. 2012;49(3):451–58. Slideshow Project DOI: /JRRD JSP Single session of brief electrical stimulation immediately following crush injury enhances functional recovery of rat facial nerve Eileen M. Foecking, PhD; Keith N. Fargo, PhD; Lisa M. Coughlin, MD; James T. Kim, MD; Sam J. Marzo, MD; Kathryn J. Jones, PhD

This article and any supplementary material should be cited as follows: Foecking EM, Fargo KN, Coughlin LM, Kim JT, Marzo SJ, Jones KJ. Single session of brief electrical stimulation immediately following crush injury enhances functional recovery of rat facial nerve. J Rehabil Res Dev. 2012;49(3):451–58. Slideshow Project DOI: /JRRD JSP Aim – Test whether electrical stimulation (ES) adminis- tered immediately after crush injury further decreases time for complete recovery from facial paralysis. Relevance – Peripheral nerve injuries lead to various conditions, including paresis or paralysis. – Daily ES to facial nerve proximal to injury affects early events in nerve regeneration process in rats by initiating axon sprout formation.

This article and any supplementary material should be cited as follows: Foecking EM, Fargo KN, Coughlin LM, Kim JT, Marzo SJ, Jones KJ. Single session of brief electrical stimulation immediately following crush injury enhances functional recovery of rat facial nerve. J Rehabil Res Dev. 2012;49(3):451–58. Slideshow Project DOI: /JRRD JSP Methods Rats received unilateral facial nerve crush injury. – Electrode positioned on nerve proximal to injury. Rats received 30 min of ES daily for: – 1 d (day of injury), 2 d, 4 d, 7 d, or daily until complete functional recovery. – Untreated animals received no ES. Rats were observed daily for return of facial function.

This article and any supplementary material should be cited as follows: Foecking EM, Fargo KN, Coughlin LM, Kim JT, Marzo SJ, Jones KJ. Single session of brief electrical stimulation immediately following crush injury enhances functional recovery of rat facial nerve. J Rehabil Res Dev. 2012;49(3):451–58. Slideshow Project DOI: /JRRD JSP Results One session of ES was as effective as daily stimulation at enhancing recovery of most functional parameters.

This article and any supplementary material should be cited as follows: Foecking EM, Fargo KN, Coughlin LM, Kim JT, Marzo SJ, Jones KJ. Single session of brief electrical stimulation immediately following crush injury enhances functional recovery of rat facial nerve. J Rehabil Res Dev. 2012;49(3):451–58. Slideshow Project DOI: /JRRD JSP Conclusions Use of one 30 min session of ES should be studied as possible treatment strategy for human patients with paralysis as result of acute nerve injuries.