The Basic Science of Periprosthetic Osteolysis* by Michael J. Archibeck, Joshua J. Jacobs, Kenneth A. Roebuck, and Tibor T. Glant J Bone Joint Surg Am.

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Presentation transcript:

The Basic Science of Periprosthetic Osteolysis* by Michael J. Archibeck, Joshua J. Jacobs, Kenneth A. Roebuck, and Tibor T. Glant J Bone Joint Surg Am Volume 82(10): October 1, 2000 ©2000 by The Journal of Bone and Joint Surgery, Inc.

Radiograph demonstrating extensive osteolysis in the proximal part of the femur in a patient with a cemented total hip replacement. Michael J. Archibeck et al. J Bone Joint Surg Am 2000;82:1478 ©2000 by The Journal of Bone and Joint Surgery, Inc.

Photomicrograph of chromium orthophosphate hydrate-rich corrosion products around the rim of the bore of a cobalt-chromium-alloy femoral head that was coupled with a titanium-alloy stem (× 7). Michael J. Archibeck et al. J Bone Joint Surg Am 2000;82:1478 ©2000 by The Journal of Bone and Joint Surgery, Inc.

Photomicrograph of chromium orthophosphate hydrate-rich corrosion products circumscribing the neck of a cobalt-chromium-alloy femoral component, just distal to the head-neck junction (× 5). Michael J. Archibeck et al. J Bone Joint Surg Am 2000;82:1478 ©2000 by The Journal of Bone and Joint Surgery, Inc.

Figs. 3-A and 3-B: Photomicrographs of polyethylene particles isolated from tissues, showing spheroids (Fig. 3-A) and clusters of finer particles with bridging fibrils (Fig. 3-B). Michael J. Archibeck et al. J Bone Joint Surg Am 2000;82:1478 ©2000 by The Journal of Bone and Joint Surgery, Inc.

Figs. 3-A and 3-B: Photomicrographs of polyethylene particles isolated from tissues, showing spheroids (Fig. 3-A) and clusters of finer particles with bridging fibrils (Fig. 3-B). Michael J. Archibeck et al. J Bone Joint Surg Am 2000;82:1478 ©2000 by The Journal of Bone and Joint Surgery, Inc.

Autoradiograph of Northern blot analysis, showing the expression of mRNAs for procollagen a1(I) and a2(III) in human MG-63 osteoblast-like cells incubated for forty-eight hours with various particles at a concentration of 0.05 percent. Michael J. Archibeck et al. J Bone Joint Surg Am 2000;82:1478 ©2000 by The Journal of Bone and Joint Surgery, Inc.

Photomicrographs of periprosthetic interfacial tissue removed from patients with failed cementless (Fig. 5-A) and cemented (Fig. 5-B) total hip replacements. Michael J. Archibeck et al. J Bone Joint Surg Am 2000;82:1478 ©2000 by The Journal of Bone and Joint Surgery, Inc.

Photomicrographs of periprosthetic interfacial tissue removed from patients with failed cementless (Fig. 5-A) and cemented (Fig. 5-B) total hip replacements. Michael J. Archibeck et al. J Bone Joint Surg Am 2000;82:1478 ©2000 by The Journal of Bone and Joint Surgery, Inc.