PProgeria means premature aging. IIt comes from the Greek word progeros. ‘Pro’ meaning before, and ‘geras’ meaning old age.
TThe gene for progeria is unknown but believed to be dominant. CChildren with progeria have a mutation on the gene that encodes Lamin A, a protein that holds the nucleus of the cell together. IIt’s believed that the defective Lamin A causes the nucleus of the cell to become unstable.
Progeria appears to occur without cause. It is not seen in siblings of affected children.
Children with Progeria are born looking healthy. When they are about 10 to 24 months old, features of accelerated aging start to appear. Signs of Progeria may include: Growth failure Loss of body fat Loss of hair Skin starts to look aged Stiffness in the joints Hip dislocation Heart problems Stroke
Experts do not believe that Progera is hereditary. It is due to a rare gene change which happens purely by chance. So It’s hard to say is heredity. In about 1 in every 100 cases is passed down to the next generation within the same family.
There is no for sure cure but they have found something to slow it down. They’re doing their best to find a way to stop it completely but they’re yet to figure it out for sure.
Progeria affects approximately 1 in million newborns. There are an estimated children living with Progeria worldwide at any one time. It affects both sexes equally and all races.
Progeria patients generally die between the ages of 8 and 21 - with the average age being 13.
The most common cause of progeria will not show up on a karyotype; it is a point mutation of a gene on chromosome one.
People with progeria can do things just like normal people, but for them their is a down fall because where their bodies are aging so much faster they mostly all are getting arthritis in their joints, and very stiff muscles which causes them pain.
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