Teachable Tidbit: Mobility of membrane lipids and proteins I.Pre-assessment group discussion II.Lecture/discussion/ Experimental examples III.Post unit.

Slides:

Advertisements

Similar presentations

Plasma Membrane.

Advertisements

Honors Biology Chapter 7Section 3 Cell Boundaries

Plasma Membrane  Outer boundary of a cell  Gatekeeper - controls what enters and leaves the cell.

BIO 402/502 Advanced Cell & Developmental Biology I

human eye, no microscope

Chemistry: An Introduction to General, Organic, and Biological Chemistry, Twelfth Edition© 2015 Pearson Education, Inc Cell Membranes Substances.

Cell and Developmental Biology Biology 52 Section 7 Fall Semester, 2002 Tues, Thurs 9: :45 am Coker Hall 201 Syllabus make sure you download the.

Chapter 7: Cells.  1) Regulates what goes in and out  (selectively permeable- some molecules too large or too strongly charged to cross while others.

Warm-Up #2 10/30/12 1) What does this picture represent? 2) What does hydrophilic mean? Hydrophobic? 3) What does selective permeability mean? 4) Where.

Lipids & Cell Membranes

Effects of Cholesterol on Membranes: Physical Properties Removes gel to liquid crystal phase transition New “intermediate” phase called liquid ordered.

Biological Membranes.

Cell Structure & Function Part 1

THE CELL MEMBRANE The boundary of the cell is called the cell membrane . It is also called Plasma membrane.

BC368 Biochemistry of the Cell II

Functions of the Nucleus 1. Role in cell division. 2. Influences cytoplasmic events. 3. Contains codes for protein synthesis.

Biological Membranes. Lipid Bilayer Phospholipids form bilayers in water Fluid mosaic model of membrane structure Membrane is only 10 nm thick Proteins.

Cell Membranes Semi-permeable Lipid bilayer. Function of Plasma Membrane  Physically separates cell from outside world  Maintains homeostasis  Regulates.

Plasma Membrane. Cell Membrane 1. What is the special lipid found in the plasma membrane? 2. What do you think makes up the plasma membrane?

Parts of the Eukaryotic Cell Eukaryotic cells generally have three main components I.A cell membrane.

Membrane Proteins FOB Guided Exploration 9.

The cell membrane is a phospholipid bilayer. Sometimes you will hear it referred to as a “fluid mosaic”.

The Plasma Membrane Section 7.2 p

Cell membrane. Good morning Good morning Get your homework out so I can collect it You have a quiz over cells and viruses today.

com/watch?v=Pfu1D E9PK2w CELL MEMBRANE.

The hydrophobic effect drives the aggregation of amphiphilic lipids in water Polar head groups Hydrophobic tails.

Membrane dynamics Degree of fluidity is similar in all membranes –Cells regulate composition based on growth conditions.

Cell Membranes.

Honors Biology.  BIG biological molecules ◦ Made of smaller parts  Monomers  Carbon-based (organic) ◦ Carbohydrates ◦ Nucleic acids ◦ Proteins ◦ Lipids.

4-2 Parts of the Eukaryotic Cell Part 1. Cell Biology or Cytology Cyto = cell ology = study Uses observations from several types of microscopes to create.

The Plasmamembrane and Lipid Rafts 08/2007 Lecture by Dr. Dirk Lang Dept. of Human Biology UCT Medical School Room Phone:

4.3: The Plasma Membrane. Functions of the Plasma Membrane Allows only certain molecules to enter or leave Separates inside from outside Allows waste.

Section 7-3 Cell Boundaries. Plasma Membrane or Cell Membrane The boundary between the cell and its environment. Controls what enters and leaves the cell.

Cell Boundaries 7-3 The beginning and the end… 1. All cells have a cell membrane –Thin –Flexible 2. Some cells have additional support known as the cell.

Part 1: Overview of Cells, Cell Membrane.  Basic unit of structure & function  200 different cell types  Made of C, O, H, N + trace elements  3 main.

Tutorial 4 Introduction - membranes.

General, Organic, and Biological Chemistry Copyright © 2010 Pearson Education, Inc.1 Chapter 17 Lipids 17.8 Cell Membranes.

What is a membrane? A water-induced structure composed of a lipid bilayer and integral and peripheral proteins A water-induced structure composed of a.

Cell Membrane Structure and Function Cell Membrane Structure Pg. 95 A.Function 1.Allows for movement into and out of the cell 2.Protection / Support.

Biology 205 Lecture 05: Membranes Readings: DO NOT POST THESE LECTURES!!! INSTRUCTOR VERSIONS.

Name the following structures:

MEMBRANE PERMEABILITY

17.7 Cell Membranes Substances are transported across a cell membrane by either diffusion, facilitated transport, or active transport. Learning Goal.

Lecture 5: Membrane structure

Plasma Membrane.

Part 1: Overview of Cells, Cell Membrane

Cell (plasma) Membrane

Modern Day Eukaryotic Cells

Part 1: Overview of Cells, Cell Membrane

Draw and label the parts of the cell membrane.

الفصل 3: الخلايا وتركيبها ووظائف اجزائها cells structure & Functions

Chapter 3: Cells.

Biological Membranes Sections

Cell Membrane Plasma Membrane Phospholipid Bilayer Semipermeable Membrane Ch

WEEK 12 VOCABULARY CYTOPLASM NUCLEOLUS NUCLEAR MEMBRANE NUCLEAR PORES

Supplementary Figure 1 A. B..

Do Now What is the role of the cell membrane?

INTRODUCTION TO THE CELL

3.3 Cell Membrane.

Read pgs Complete Review QUESTIONS

Honors Biology Class Standard Explain the role of cell organelles for both prokaryotic and eukaryotic cells, including the cell membrane, in maintaining.

Honors Biology Class Standard Explain the role of cell organelles for both prokaryotic and eukaryotic cells, including the cell membrane, in maintaining.

The Plasma Membrane.

Cell Membrane notes.

The Plasma Membrane.

Presentation transcript:

Teachable Tidbit: Mobility of membrane lipids and proteins I.Pre-assessment group discussion II.Lecture/discussion/ Experimental examples III.Post unit assessment: problem set and quiz

The fluid mosaic model for biological membranes: A lipid bilayer within which integral membrane proteins are inserted into and through the bilayer, but unless restrained, free to move within the plane of the membrane.

Topic/unit objective: Understanding the nature of and functional significance of the dynamics of lipids and proteins in biological membranes Pre-unit assessment goal: How would you demonstrate the mobility of lipids and/or proteins in biological membranes? CRAZY IDEAS WELCOME: Fluid Mosaic Model for Biological Membranes

I.Modes of lipid mobility; factors that affect mobility II.Topographic organization of biological membrane proteins III.Lateral mobility of integral membrane proteins I.Frye and Edidin experiment demonstrating lateral mobility of cell surface proteins in mouse/human heterokaryons II.Antibody “capping” of cell surface membrane proteins III.Kinetic analysis of lateral membrane protein mobility: FRAP and FLIP analysis IV.Modes of regulating membrane protein mobility

Fluorescence Recovery after Photobleaching (FRAP)

Fluorescence recovery after photobleaching

Nuclear lamina on inner surface of frog egg nucleus. Lamin dimers