Ann M. Hoff, MD ETC Physician Trinity Health
American Stroke Association Guidelines for the Early Management of Adults with Ischemic Stroke (2007) “Time is Brain”
Stroke Facts In the US, someone has a stroke every 40 seconds Every 3-4 minutes, someone dies of stroke > 700,000 strokes and > 150,000 stroke deaths each year Stroke is the 3 rd leading cause of death
Stroke is the leading cause of long-term disability Ischemic strokes account for 85% of all strokes In 2009, stroke cost the US $68.9 billion
Stroke Signs/Symptoms 5 most common signs/symptoms Sudden numbness/weakness of the face, arm, or leg Sudden confusion or trouble speaking or understanding Sudden trouble seeing in one or both eyes Sudden dizziness, trouble walking, or loss of balance/coordination Sudden severe headache with unknown cause
Stroke Risk – Race/Ethnicity African Americans have the double the risk of stroke in comparison to Caucasians Hispanic Americans fall between Caucasians and African Americans African and Hispanic Americans are more likely to die following a stroke than are Caucasians
Stroke Risk - Age Nearly one quarter of strokes occur in people under the age of 65
Stroke Risk Factors In 2003, approximately 37% of adults reported having two or more of the risk factors listed above.
US Stroke Map
Hospitalizations
Mortality
ND Hospitalizations
ND Mortality
Prehospital Management EMS Utilization 29-65% 62-95% of EMS activations occurred by an individual other than the patient Dispatcher identified 52% of patients ultimately proven to have had a stroke on the initial telephone conversation
19-60% present within 3 hrs 14-32% present within 2 hrs Decreased time to physician exam, CT, and neuro evaluation
EMS Care Rapid identification of stroke Identification of possible stroke mimics 19-31% ABCs Transport Notify ER
Community Ambulance
Cincinnati Stroke Scale
ACT F.A.S.T. Facial Droop Arm Weakness Speech Time
Golden Hour of Stroke
Emergency Room Care The First 15 Minutes Acute Stroke Protocol ○ Focused H&P ○ NIHSS ○ Labs ○ IVs ○ EKG ○ Weight ○ Alert pharmacy to possible need for tPA ○ Order CT scan
Stroke Alert Team Response ER MD Neuro MD Recorder EKGCT TECHLAB Radiologist
Clinical Assessment mY33Hhc&feature=player_embedded#! mY33Hhc&feature=player_embedded#
Treatment Emergency Treatment Based on results of head CT and time of symptom onset
No blood on CT, < 3hrs from onset Review inclusion/exclusion criteria Obtain consent If tPA given, admit to ICU for 24 hrs
No blood on CT, > 3hrs & < 8 hrs Off-label IV tPA up to 4.5 hrs Further imaging may expand treatment options: ○ CT angiogram IA tPA Mechanical thrombectomy -MERCI clot retrieval system (8/2004) -Penumbra system (12/2007)
No blood on CT, > 8 hrs 325 mg of aspirin ○ Reduces early death ○ Reduces long-term disability
Prevention 1 in 8 stroke survivors will have another stroke within 5 years Treatment of underlying cause is important Education Rehabilitation PT/OT to relearn skills
Resources Management of Ischemic Stroke: Part 1. Emergency Room Management. Journal of Hospital Medicine. Vol 5; No1; January Guidelines for the Early Management of Adults with Ischemic Stroke. Stroke 2007, 38: ; April 12, CDC American Heart Association American Stroke Association National Stroke Association Mayo Clinic Genentech