بسم الله الرحمن الرحیم.

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بسم الله الرحمن الرحیم

Pons

- The posterior surface is limited laterally by the superior cerebellar peduncles and is divided into symmetrical halves by a median sulcus. - Lateral to this sulcus is an elongated elevation, the medial eminence, which is bounded laterally by a sulcus,the sulcus limitans - The inferior end of the medial eminence is slightly expanded to form the facial colliculus, which is produced by the root of the facial nerve winding around the nucleus of the abducent nerve - The floor of the superiorp art of the sulcus limitans is bluish-gray in color and is called the substantia ferruginea; it owes its color to a group of deeply pigmented nerve cells. - Lateral to the sulcus limitans is the area vestibuli produced by the underlying vestibular nuclei.

Pons For purposes of description, the pons is commonly divided into a posterior part, the tegmentum, and an anterior basal part by the transversely running fibers of the trapezoid body Tegmentum of pons directed upward continuation of medulla oblongata Basilar part contains both longitudinal and transverse fibers intermixed with pontine nuclei

Isfahan Medical Faculty, Anatomical Sciences Department 1386 Isfahan Medical Faculty, Anatomical Sciences Department

- The medial longitudinal fasciculus is situated beneath the floor of the fourth ventricle on either side of the midline. - The medial longitudinal fasciculus is the main pathway that connects the vestibular and cochlear nuclei with the nuclei controlling the extraocular muscles (oculomotor, trochlear and abducent nuclei).

- The medial longitudinal fasciculus is situated beneath the floor of the fourth ventricle on either side of the midline. - The medial longitudinal fasciculus is the main pathway that connects the vestibular and cochlear nuclei with the nuclei controlling the extraocular muscles (oculomotor, trochlear and abducent nuclei).

Trapezoid body formed by auditory fiber that decussate Superior olivary n in the auditory tract Locus coeruleus neuradernergic Raphene n (ascending fiber) sleep(insomnia) Raphespinal decrease pain

Midbrain

On the posterior surface: are four colliculi (corpora quadrigemina) These are rounded eminences that are divided into superior and inferior pairs by a vertical and a transverse groove The superior colliculi are centers for visual reflexes and the inferior colliculi are lower auditory centers. ln the midline below the inferior colliculi, the trochlear nerves emerge. These are small diameter nerves that wind around the lateral aspect of the midbrain to enter the lateral wall of the cavernous sinus.

On the anterior aspect of the midbrain (Fig On the anterior aspect of the midbrain (Fig.5-23),there is a deep depression in the midline, the interpeduncular fossa, which is bounded on either side by the crus cerebri. Many small blood vessels perforate the floor of the interpeduncular fossa and this region is termed the posterior perforated substance. The oculomotor nerve emerges from a groove on the medial side of the crus cerebri and passes forward in the lateral wall of the cavernous slnus..

On the lateral aspect of the midbrain, the superior and inferior brachia ascend in an anterolateral direction. The superior brachium passes from the superior colliculus to the lateral geniculate body and the optic tract. The inferior brachium connects the inferior colliculus to the medial geniculate body.

Internal structure of the midbrain

Transverse Section of the Midbrain at the Level of the Inferior Colliculi The substantia nigra is a large motor nucleus situated between the tegmentum, and the crus cerebri and is found throughout the midbrain. The nucleus is composed of medium-size multipolar neurons that possess inclusion granules of melanin pigment within their cytoplasm. The substantia nigra is concerned with muscle tone and is connected to the cerebral cortex,spinal cord, hypothalamus, and basal nuclei.

Isfahan Medical Faculty, Anatomical Sciences Department 1386 Isfahan Medical Faculty, Anatomical Sciences Department

Transverse Section of the Midbrain at the Level of the superior Colliculi The red nucleus is a rounded mass of gray matter situated between the cerebral aqueduct and the substantia nigra. Its reddish hue, seen in fresh specimens,is due to its vascularity and the presence of an ironcontaining pigment in the cytoplasm of many of its neurons. Afferent fibers reach the red nucleus from: (1) the cerebral cortex through the corticospinal fibers ( 2) the cerebellum through the superior cerebellar peduncle, and (3) the lentiform nucleus subthalamic and hypothalamic nuclei,substantia nigra,and spinal cord Efferent fibers leave the red nucleus and pass to (1) the spinal cord through the rubrospinal tract (as this tract descends,it decussates), (2) the reticular formation through the rubroreticular tract, (3) the thalamus and (4) the substantia nigra.

Midbrain Tectum of midbrain: includes superior and inferior colliculi Cerebral peduncle Tegmentum : contain ascending tracts, central gray matter, recticular formation and so on Substantia nigra Crus cerebri : Pyramidal tract- middle three-fifths of the crus: Frontopontine tract medial one-fifth: pariatotempopontine tract lateral one-fifth

Substantia nigra(melatonin) motor activities Degeneration of S.N parkinson s disease

Isfahan Medical Faculty, Anatomical Sciences Department 1386 Isfahan Medical Faculty, Anatomical Sciences Department

Isfahan Medical Faculty, Anatomical Sciences Department 1386 Isfahan Medical Faculty, Anatomical Sciences Department

Isfahan Medical Faculty, Anatomical Sciences Department Trigeminal Tract 1386 Isfahan Medical Faculty, Anatomical Sciences Department

Isfahan Medical Faculty, Anatomical Sciences Department 1386 Isfahan Medical Faculty, Anatomical Sciences Department

Isfahan Medical Faculty, Anatomical Sciences Department Trigeminal Tract Lesion in trigeminal nucleus : Face anesthesia Lesion in trigeminal lemniscus : Contral lateral Face anesthesia 1386 Isfahan Medical Faculty, Anatomical Sciences Department