Major risk factors for PRRS in Colombian farms Dr. Derald Holtkamp Cartagena, July 16, 2014

Outline Importance of biosecurity and need for tools to assess risk Production Animal Disease Risk Assessment Program (PADRAP) Assessment of risks in Colombian sow farms

In the U.S. PRRSV had been the primary disease that motivated producers to improve biosecurity “wake up call” Introduction of porcine circovirius type 2 (PCV2) and porcine epidemic diarrhea virus (PEDV) has been a real “wake up call” Biosecurity! Biosecurity! Biosecurity! Photo: Courtesy of Dr. Matt Ackerman

PEDV spread rapidly between and within regions of the U.S. Biosecurity as currently practiced in the U.S. was NOT effective at slowing the spread of the virus Source: Swine Enteric Coronavirus Disease Testing Summary Report, USDA Animal Plant & Health Inspection Service, May 15, 2014.

And now porcine deltacoronavirus (PDCoV) Source: Swine Enteric Coronavirus Disease Testing Summary Report, USDA Animal Plant & Health Inspection Service, May 15, 2014.

~50% of sow herds infected with PEDV Source: Swine Health Monitoring Report, University of Minnesota, College of Veterinary Medicine. March 7, ~50%

But… PRRSV was relatively quiet this year Source: PRRS incidence study update, University of Minnestota, March 19, 2014

The slow down in PRRS dates back to July 2013 July 2013 Source: PRRS incidence study update, University of Minnestota, March 19, 2014

Biosecurity is the primary tool to slow herd-to-herd transmission and prevent outbreaks Biosecurity! Biosecurity! Biosecurity!

But – making continuous improvements in biosecurity is hard Disease risk is complicated (and frequently overwhelming) Requires effort and costs money – must be tailored to circumstances of farm Can’t do everything – have to start somewhere

Giving producers published lists of biosecurity recommendations or “page- after-page” of protocols doesn’t work! Need tools to assess risks and implement biosecurity that is tailored for farms or production systems

Outline Importance of Biosecurity and need for tools to assess risk Production Animal Disease Risk Assessment Program (PADRAP) Assessment of risks in Colombian sow farms

Production Animal Disease Risk Assessment Program (PADRAP) is a program through which a set of disease risk assessment surveys are delivered PADRAP is owned by The American Association of Swine Veterinarians (AASV) and is used by veterinarians who are members

Surveys can be delivered through PADRAP

“Risk Quadrant” report Enables benchmarking of disease risks Examples of reports

Enables benchmarking of disease risks Examples of reports “Individual Risk Factor” report

PADRAP is provided as a benefit to members of AASV No fees for using PADRAP Must be an AASV member to access it – International (Associate) members are eligible to use the program

History of Development Fall-2002: Fall-2002: Design and development of the PRRS Risk Assessment for the Breeding Herd was done at Boehringer Ingelheim Vetmedica Inc. (BIVI) March 2005: March 2005: BIVI offered to gift the tool to the American Association of Swine Veterinarians (AASV) March 2006: March 2006: AASV, with support from National Pork Board (NPB) and USDA accepted the gift September 2006: Production Animal Disease Risk Assessment Program (PADRAP) September 2006: Iowa State University College of Veterinary Medicine, Food Supply Veterinary Medicine entered into an agreement with AASV to establish the Production Animal Disease Risk Assessment Program (PADRAP)

History of Development November 2007: November 2007: Launch of web version – “PADRAP-Online” February 2008: February 2008: PADRAP Advisory Committee created March 2009: March 2009: Growing Pig Assessment introduced December 2011: December 2011: Boehringer Ingelheim, Harrisvaccines, NPPC and Newport Laboratories become sponsors of PADRAP

Collaborative effort – American Association of Swine Veterinarians (AASV) – Iowa State University (ISU) providing program coordination and web hosting Director: Derald Holtkamp Associate Director: Chris Mowrer – Financial support National Pork Board (NPB) Boehringer Ingelheim Vetmedica Inc. (BIVI) Harrisvaccines National Pork Producers Council (NPPC) Newport Laboratories

Training sessions conducted 363: Number of veterinarians that have been trained – 67 – 67 training sessions (33 online; 34 face-to-face) have been conducted in the U.S., Canada, Mexico, Colombia, Serbia and online – Used primarily by veterinarians and researchers in the U.S, Mexico and Canada – Veterinarians from Australia, Bermuda, Chile, Colombia, Germany, Italy, Japan, Netherlands, Philippines, Serbia, South Korea and UK have also been trained Veterinarians are provided a username and password for the web version that is activated upon completion of training

Database of PRRS Risk Assessment for the Breeding Herd (version 2) continues to grow – 3,678: Number of assessments completed (as of February 2014) – 1,878: Number of breeding herd sites assessed (as of February 2014) PRRS Risk Assessment for the Breeding Herd

PRRS Risk Assessment for the Growing Pig Herd Database of PRRS Risk Assessment for the Growing Pig Herd (version 1) – 1,120: Number of assessments completed (as of February 2014) – 982: Number of growing pig sites assessed (as of February 2014)

Ways veterinarians have applied the PRRS Risk Assessment for the Breeding Herd Evaluate current biosecurity protocols and/or to develop new biosecurity protocols Demonstrate improvement in biosecurity over time to help justify expenditure of resources on biosecurity An aid in the decision to initiate a project to eliminate PRRSV from a breeding herd site Regional PRRS Elimination / control projects utilizing PADRAP

Steps to get access to and use PADRAP Become member of AASV Attend an AASV training session (username and password provided at end of training) Set up “production system(s)” and “site(s)” in PADRAP Create and complete risk assessment surveys View risk benchmarking reports

Outline Importance of Biosecurity and need for tools to assess risk Production Animal Disease Risk Assessment Program (PADRAP) Assessment of risks in Colombian sow farms

PRRS Control and Monitoring Program in Colombia Coordinated by the Technical Area of the Colombian Association of Pork Producers (Asociación Colombiana de Porcicultores) – Jose Fernando Naranjo – Diego Rodriguez – Mayra Aguirre – Natalia Toro A PADRAP training session was conducted in Colombia – Lilly Urizar with Centre de développement du porc du Québec (CDPQ)

72 sow herds in Colombia were assessed between July of 2013 and June of 2014

Average risk scores for Colombian farms assessed vs. average of all sites in the database (Benchmarked Against) “Biosecurity” terminology External Risks => Bioexclusion External Risks => Bioexclusion – keeping pathogens out of a population Internal Risks => Biomanagement Internal Risks => Biomanagement – managing pathogens already in a population to minimize the negative consequences Dr. Butch Baker, National Hog Farmer, 10/15/2009

Average risk scores for Colombian farms assessed vs. average of all sites in the database (Benchmarked Against) “Big bar bad --- little bar good” Opportunity is to improve bioexclusion

Smaller and mid-size sow herds tended to have more frequent outbreaks

Farrow-to-finish farms had more frequent outbreaks

Most of the sow herds that were assessed were PRRSV “naïve” or “negative” Holtkamp et. al Terminology for classifying swine herds by PRRS virus status. J. Swine Health Prod. 19:

Closed herds (produce their own gilts) and farms with more sources of replacement gilts had more frequent outbreaks

Sow herds that obtained gilts from herds that were positive unstable or unknown status had more frequent outbreaks

Sow herds that enter gilts without routinely testing for PRRSV by PCR or ELISA had more frequent outbreaks

Just over ½ of the sow herds assessed are bringing semen in from outside the farm

Sow herds that received semen from boar studs with unknown PRRSV status had more frequent outbreaks

Sow herds that did not know when the most recent outbreak had occurred at the boar stud(s) had more frequent outbreaks

Of the assessed sow farms that are bringing in semen from outside the farm, very few are testing boars for PRRSV by PCR

When sow herds did not wash vehicles that hauled pigs between every load they had more frequent outbreaks

When sow herds did not allow vehicles that hauled genetic replacements to dry after washing they had more frequent outbreaks

Nearly all of the sow farms assessed disposed of dead animals on-site

Sow farms that only required a boot wash / disinfection or with unrestricted entry had more frequent outbreaks

Sow farms with high employee turnover had more frequent outbreaks

Sow farms located in areas with more swine farms had more frequent outbreaks

Sow farms located on flat land or gentle rolling hills had more frequent outbreaks

Acknowledgements American Association of Swine Veterinarians National Pork Board PADRAP Sponsors –Boehringer Ingelheim Vetmedica, Inc. –Harrisvaccines –NPPC –Newport Laboratories Asociación Colombiana de Porcicultores – Jose Fernando Naranjo – Diego Rodriguez – All the veterinarians and producers that completed the PADRAP questionnaires