WP11: Modelling and simulation for NND WP Leader: Motek Medical Peter Martens, Frans Steenbrink Amsterdam – February 2015

Status of the WP T11.1 Construction of a scalable mass distribution model suitable for the paediatric population [M 1-48] – Complete data set for development pipeline (Vumc, KUL and OPBG (incl MRI)) – Method for functional joint calibration developed and implemented in products – New joint rotation centers > TUD for scaling – Product development Amsterdam – February 2015

Brussels – 6-7 May 2014

Functional joint center calibration Brussels – 6-7 May 2014 Functional calibration (video in lab Leuven) Visualization done using MITK MITK.org

Functional joint center calibration Brussels – 6-7 May 2014 Functional calibration (video) Visualization done using MITK MITK.org

Functional joint center calibration Brussels – 6-7 May 2014 Functional calibration (video) Visualization done using MITK MITK.org

Offline Analysis Tool Brussels – 6-7 May 2014 GOAT – video overlay (video) Visualization done using MITK MITK.org

Status of the WP T11.1 Construction of a scalable mass distribution model suitable for the paediatric population [M 1-48] – Method for functional joint calibration developed and implemented in products – New joint rotation centers > TUD for scaling – Product development T11.2 Development of a personalized disease specific skeletal model [M 12-48] – Musculoskeletal Human Body Model adaptations Marker set-up > pose dependent > functional calibration Pipeline to reconstruct HBM with different skeletal (HBM) and muscle parameters (via OpenSIM) Amsterdam – February 2015

Status of the WP T11.1 Construction of a scalable mass distribution model suitable for the paediatric population [M 1-48] – Method for functional joint calibration developed and implemented in products – New joint rotation centers > TUD for scaling – Product development T11.2 Development of a personalized disease specific skeletal model [M 12-48] – Musculoskeletal Human Body Model adaptations Market set-up > pose dependent > functional calibration Pipeline to reconstruct HBM with different skeletal (HBM) and muscle parameters (via OpenSIM) T11.3 Construction of a disease specific muscle model [M1-36] – Musculoskeletal Human Body Model adaptations Investigate pipeline to change muscle dynamics (spasticity model needed) Amsterdam – February 2015

Status of the WP T11.1 Construction of a scalable mass distribution model suitable for the paediatric population [M 1-48] – Method for functional joint calibration developed and implemented in products – New joint rotation centers > TUD for scaling – Product development T11.2 Development of a personalized disease specific skeletal model [M 12-48] – Musculoskeletal Human Body Model adaptations Market set-up > pose dependent > functional calibration Pipeline to reconstruct HBM with different skeletal (HBM) and muscle parameters (via OpenSIM) T11.3 Construction of a disease specific muscle model [M1-36] – Musculoskeletal Human Body Model adaptations Investigate pipeline to change muscle dynamics (spasticity model needed) T11.4 Design of models driven by the dynamics of gait perturbations [M12-36] – Development of walking speed variation protocol using a self-selected treadmill mode Measure nonlinear changes in joint moments > muscle activity Amsterdam – February 2015

T11.4 Design of models driven by the dynamics of gait perturbations [M12-36] Brussels – 6-7 May 2014 Speed variations application (video)