Behringhauser Str Castrop-Rauxel GERMANY Tel. +49 – – Fax +49 – –

Nordrhein-Westfalen one of 16 states in Germany 20 Million people in 150 miles x 150 miles WORLD-CLASS MRI + iMRI Research - Aachen - Bochum - Cologne - Bonn - Münster - Essen - Düsseldorf - Gelsenkirchen - plus many more

Mission Statement: Develop MRI implants and interventional devices based on a huge dedicated patent portfolio. Introduce commercial products through development, via strategic joint ventures, and licensing agreements with major companies having marketing and development expertise. Provide marketing and technical support to various partners to assure commercial success. Position BIOPHAN as a development leader for MRI implants and interventional MRI devices and procedures. Located in Castrop-Rauxel and Gelsenkirchen, Germany with an extensive R&D network, cooperations with some of the worlds leading MRI research groups, internal development laboratories and MRI systems.

0.3 Tesla unit and 1.0 Tesla unit Access to 1.5 Tesla units of all OEM Access to 3 Tesla in Münster in Aachen Access to 7 Tesla in Essen Government funded research Excellent network to many research institutions Consultant contracts with many of the worlds leading interventional MRI experts Ongoing research programs with the universities of Gelsenkirchen, Aachen, Essen Scientific presentations in most upcoming MRI meetings

aMRIs active MRI marker / guidewire aMRIs Tantalum BX Stent Plus : Occluder Catheter Tools aMRIs ™ Technology -- Prof. Melzer

aMRIs Nitinol SX Stent (in cooperationwith ADMEDES and NDC) aMRIs Nitinol Vena Cava Filter (in cooperation with ADMEDES and NDC) aMRIs Polymer Stent THROMBUS aMRIs ™ Technology --> Prof. Melzer

AACHEN RESONANCE™ Technology -- Prof. Bücker

University Clinic Aachen Animal Lab Angio Operating Room 1.5 T XMR Research Scanner Cath Lab Radiology Research Partner