هو العلیم. Connective Tissue Constituencies of Connective Tissue Cell Fibers Ground Substance.

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Presentation transcript:

هو العلیم

Connective Tissue

Constituencies of Connective Tissue Cell Fibers Ground Substance

Functions of Connective Tissue Support Repair Defense Storage Thermal Insulatio n Reservoir of Hormones Controlling Growth & Differentiation

Cells of Connective Tissue Mesenchymal Cell Mesenchymal Cell Fibroblast, Fibrocyte Fibroblast, Fibrocyte Mast cell Mast cell Plasma cell Plasma cell Macrophage Macrophage Adipose cell Adipose cell Leukocytes Leukocytes

Mesenchymal Cell Undifferentiated Cell that can differentiate to the other cell type in connective tissue

Fibroblast

Fibroblast

Fibrocyte

Difference Between the Fibrocyte and Fibroblast

Mast Cell

IGE Histamin, Heparin, Leukoterian Eosinophil Chemotactant Factor Anticoagolant Increase Vascular Permeability Slow reacting substance of Anaphylaxis Histaminase, Arylsulfatas e

Mast Cell

Plasma Cell

Macrophage & Plasma Cell

Macrophage Phagocytosis Phagocytosis Antigen Presenting Antigen Presenting Secretion of Cytokines Secretion of Cytokines Fe & Fat Metabolism Fe & Fat Metabolism Destruction of Aged Erythrocytes Destruction of Aged Erythrocytes Cell Mediated Resistance Cell Mediated Resistance

Chemical Mediators of inflammation Diapedesis Increase Blood flow (Histamine) Increase Blood flow (Histamine) Vascular Permeability Vascular Permeability  Local Swelling, Redness, Heat, Pain Chemotaxis Chemotaxis Phgocytosis Phgocytosis

Adipose Cell

Fibers Collagen Collagen Reticular Reticular Elastic Elastic

Collagen Fibers

Types of Collagen Fibers Collagen that form long fibers (I, II, III, V, XI) Collagen that form long fibers (I, II, III, V, XI) Fiber associated collagen (IX, XII, XIV) Fiber associated collagen (IX, XII, XIV) Collagens that form networks (IV) Collagens that form networks (IV) Collagens that form anchoring fibers (VII) Collagens that form anchoring fibers (VII) Epithelial Associated Collagen (VIII) Epithelial Associated Collagen (VIII)

Collagen Biosynthesis

Biosynthesis of collagen type I

Reticular Fiber

Elastic Fiber

Type of Elastic Fibers Fibrillin Fibrillin Oxytalan Oxytalan Elaunin Elaunin Elastic Elastic

Elastic Fiber

Elastin

Ground Substance Proteoglycan Proteoglycan Glycoprotein Glycoprotein

Glycosaminoglycans Hyalouronic Acid Aggrecan Ground substance component

Proteoglycan & Glycoprotein

The way of the attachment of the cytoskeleton to the extracellular matrix

Types of connective tissue Connective tissue proper Connective tissue proper  Loose connective tissue  Dense connective tissue  Regular  Irregular Connective tissue with special properties Connective tissue with special properties  Elastic connective tissue  Reticular connective tissue  Adipose tissue Supporting connective tissue Supporting connective tissue

Loose connective tissue

Dense connective tissue

Dense Regular Connective Tissue

Reticular Connective Tissue

Adipose connective tissue Function Function Type Type  Unilocular ( Yellow)  Multilocular (Brown)

Adipose Tissue

Unilocular Adipose Tissue

Adipose tissue Histogenesis

Brown Fat Distribution

Multilocular Adipose Tissue

Comparison of the Yellow and Brown Fat Tissue