INHALATION RISK ASSESSMENT THROUGH PASSIVE SMOKING GROUP MEMBERS: - PRAGYA AGRAWAL(2013AST2050), PRIYA (2013CEW2212), SANDEEP SARNA (2013CEW2214 ) Assistant Professor Department of Civil Engineering Indian Institute of Technology-Delhi, New Delhi (INDIA) Contact No.:
Data Collection: 142 Persons are surveyed They are divided according to Brand of Cigarette and Age. Nicotine content of each Brand and Bidis was found and Risk Analysis was done Groups Most Exposed : 6 % Nicotine Intake Least Exposed : 1 % Nicotine Intake Group A: Children under 15 yrs. Group B: Pregnant women & Group C: Adults Sr. No.EventSeverityProbability 1Children Most Exposed to ETSCatastrophicFrequent 2Children Averagely Exposed to ETSMarginalProbable 3Pergenant Lady Most Exposed to ETSCriticalFrequent 4 Pergenant Lady Averagely Exposed to ETS MarginalProbable 5Adults Most Exposed to ETSCriticalFrequent 6Adults Averagely Exposed to ETSNegligibleProbable Probability and Severity Table
Inhalation of ETS (Nicotine) by subject at public places Subject passing nearby and inhales cigarette smoke Presence of ETS (Nicotine) in the public environment Presence of Nicotine in Cigarette of Smoker Smoker smokes At Public place Inhalation of ETS (Nicotine) by subject at office premise Subject passing nearby and inhales cigarette smoke Presence of ETS (Nicotine) in the office premise Presence of Nicotine in Cigarette of Smoker Smoker smokes Inside office premise Inhalation of ETS (Nicotine) by subject at Home Subject passing nearby and inhales cigarette smoke Presence of ETS (Nicotine) in Home Presence of Nicotine in Cigarette of Smoker Smoker smokes At Home Non-Carcinogen effect of ETS (Nicotine) to a passive smoker and or Fault Tree
Parameter Distributio n of Parameter Base Hazard Quotient (low value, high value) ChildrenPregnant LadyAdults Most Exposed Avg. Exposed Most ExposedAvg. ExposedMost Exposed Avg. Exposed Cigerrette Intake (no. of Cig./day)8 (3, 17) (32.19,182.41) 3.57 (1.34, 7.6) 28.6 (10.73,60.8) 1.2 (0.44, 2.53) (5.74,32.5) 0.64 (0.24, 1.35) Nicotine Content (mg/cigerette) (In most exposed group) (0.5973, ) (79.64, ) 28.6 (26.54, 41.7) (14.22, 22.38) Nicotine Content (mg/cigerette) (In avg. exposed group) (0.0995, ) 3.57 (3.31, 5.22) 1.2 (1.1,1.74) 0.64 (0.59, 0.93) Sensitivity Index (Cig. Intake) Sensitivity Index (Nicotine Content)) Risk Characterization: Hazard Quotient Assumptions Involved: Exposure Duration for Most Exposed Group =4 Hr per Day Exposure Duration for Avg. Exposed Group=1 Hr per Day ParameterChildrenPergenant LadyAdults Body Weight (Kg) RfD of Nicotine (mg/(Kg.day)
CONCLUSIONS AND RESULTS:- Avoided zone: Chidren, Pregnant Lady and Adults (most exposed) Accepted by Waiver : Chidren, Pregnant Lady (average exposed) Routingly Accepted zone : Adults (average exposed) Effect on Children:- Most Exposed85.84High Risk (Must be Avoided) Average Exposed3.57Low Risk Effect on Pregnant Lady Most Exposed28.6High Risk (Must be Avoided) Average Exposed1.2Low Risk Effect on Pregnant Lady Most Exposed15.32High Risk (Must be Avoided) Average Exposed0.64Acceptable Risk