 Establishes a benchmark from a non- evolving population in which to measure an evolving population.  Investigates the properties of populations that are not evolving

 States that:  1. frequencies of alleles and genotypes in a population’s gene pool remain constant from generation to generation  2. provided there are no evolutionary forces at work, such as:  Genetic drift  Natural Selection  Gene Flow

 1. constant allele frequencies from one generation to the next  2. predictable genotype frequencies from allele frequencies

 1. no mutations  2. no gene flow  3. random mating  4. large population size to prevent genetic drift  5. no selection

 p= frequency of the dominant allele  q= frequency of the recessive allele  p 2 = percentage of homozygous dominant individuals  q 2 = percentage of homozygous recessive individuals  2pq= percentage of heterozygous individuals

 Tongue rolling is an autosomal dominant trait (not really but we will pretend it is)  RR = homozygous dominant  Rr = heterozygous dominant  rr= homozygous recessive

 Population of the class = ___ individuals = ___ alleles  ____ students where non tongue rollers = rr  ____ students where tongue rollers = RR, or Rr  Calculate the following:  Frequency of the “rr” genotype:  Frequency of the “r” allele:  Frequency of the “R” allele:  Frequency of the “RR” and “Rr” genotypes

 q 2 =  q=  p=  p 2 =  2pq =

 You have sampled a population in which you know that the percentage of the homozygous recessive genotype is 36%. Calculate the following:  Frequency of the “aa” genotype  Frequency of the “a” allele  Frequency of the “A” allele  Frequencies of the “AA” and “Aa” genotypes

 A very large population of randomly mating laboratory mice contains 35% white mice. White coloring is caused by the homozygous recessive genotype “aa”. Calculate allelic and genotypic frequencies for this population.