Cascada de Señalización del AMPc

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Presentation transcript:

Cascada de Señalización del AMPc

GLUCAGON/ ADRENALINA

GLUCAGON/ ADRENALINA α β γ GDP

GLUCAGON/ ADRENALINA α β γ GDP GTP GDP

GLUCAGON/ ADRENALINA β γ α GTP

GLUCAGON/ ADRENALINA β γ α GTP

GLUCAGON/ ADRENALINA β γ ADENILATO CICLASA α GTP

GLUCAGON/ ADRENALINA β γ ADENILATO CICLASA α GTP ATP AMPc + Pi

α AMPc + Pi γ ATP PKA β ADENILATO CICLASA GTP R R C C GLUCAGON/ ADRENALINA β γ ADENILATO CICLASA α GTP ATP AMPc + Pi PKA R R C C

α AMPc + Pi γ ATP PKA ADENILATO β CICLASA GTP GLUCAGON/ ADRENALINA

α AMPc + Pi γ ATP PKA ADENILATO β CICLASA GTP GLUCAGON/ ADRENALINA

α PKA Activa AMPc + Pi γ ATP ADENILATO β CICLASA GTP GLUCAGON/ ADRENALINA β γ ADENILATO CICLASA α GTP ATP AMPc + Pi AMPc AMPc PKA Activa AMPc AMPc

Fosforila otras proteínas PKA Activa Fosforila otras proteínas