Sample Size Estimation and Re- Estimation Break-out Session.

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Presentation transcript:

Sample Size Estimation and Re- Estimation Break-out Session

Format of the Session – Formation of groups to discuss topics. Identify spokesperson to feedback – Discussions – Feedback on issues raised during discussions

Topics for Discussion Group 1 (Lucy) Covariate adjustment in sample size estimation Group 2 (Nick) Accounting for missing data or treatment cross-over when sample-sizing Group 3 (Emma) Appropriate techniques for sample-size re- estimation Group 4 (Sue) Sample sizing for multiple endpoints

Issues to consider Is additional complexity warranted? Communicating relevant information Simulation versus calculation Need for guidelines? Software