Hallie Roach Communications Coordinator RACING MEDICATION AND TESTING CONSORTIUM

Established in 2002 to address the lack of uniform regulation in racing medication rules and drug testing procedures Established in 2002 to address the lack of uniform regulation in racing medication rules and drug testing procedures To develop, promote and coordinate, at the national level, policies, research and educational programs that seek to: To develop, promote and coordinate, at the national level, policies, research and educational programs that seek to: –ensure fairness and integrity of racing –ensure the health and welfare of racehorses and participants –protect the interests of the racing public Purpose and Mission “Strengthening the Integrity of Racing”

Stakeholder Organizations AAEP AAEP AQHA AQHA Arabian Jockey Club Arabian Jockey Club Breeders’ Cup Breeders’ Cup California TB Trainers California TB Trainers Churchill Downs Churchill Downs Del Mar Del Mar Hambletonian Society Hambletonian Society Harness Tracks of America Harness Tracks of America Jockeys’ Guild Jockeys’ Guild Keeneland Keeneland Kentucky TB Association Kentucky TB Association Magna Entertainment Magna Entertainment National HBPA National HBPA NTRA NTRA NYRA NYRA Oak Tree Oak Tree RCI RCI THA THA The Jockey Club The Jockey Club TOBA TOBA TB Owners of California TB Owners of California TRA TRA TRPB TRPB USTA USTA

Goals: Goals: –Uniform regulation –Level playing field –Welfare and safety of participants Implementation Strategy: Implementation Strategy: –Review existing research –New research –Scientific Advisory Committee –Consensus of directors RMTC Model of Operation

Recommended veterinary practices Recommended veterinary practices Prohibited practices Prohibited practices Drug classification system Drug classification system Restricted use of therapeutic medications: Restricted use of therapeutic medications: –Lasix and adjuncts on race day pending research –One anti-inflammatory at 24 hours before the race –Other therapeutic medications at hours Model Rules Phase 1 (2005)

Language adopted Language in the process of being adopted Process require significant legislative action Process has not been started No horse racing or harness racing commission Model Rules Adoption Progress

Three-tiered grid system Three-tiered grid system Increased penalties for illegal and performance- enhancing drugs, and lesser penalties for therapeutic medication mistakes Increased penalties for illegal and performance- enhancing drugs, and lesser penalties for therapeutic medication mistakes Re-defines trainer responsibility with extenuating circumstances “checklist” for judges Re-defines trainer responsibility with extenuating circumstances “checklist” for judges Added penalties for other responsible licensees: Added penalties for other responsible licensees: veterinarians, owners and grooms Model Rules Phase 2 (2006) Uniform Penalties

Uniform Penalties Class A – Illegal, not approved, significant performance enhancement Class A – Illegal, not approved, significant performance enhancement –Lifetime: 1st Offense – Minimum 1 year & $10,000 Maximum 3 year & $ 25,000 1st Offense – Minimum 1 year & $10,000 Maximum 3 year & $ 25,000 3rd Offense – Minimum 5 year & $ 50,000 Maximum10 year & $100,000 3rd Offense – Minimum 5 year & $ 50,000 Maximum10 year & $100,000 Class C – Therapeutic medications at less than performance enhancing levels Class C – Therapeutic medications at less than performance enhancing levels –365 Days: 1st Offense – Minimum $ 500 1st Offense – Minimum $ 500 2nd Offense – Minimum 15 day & $ 1,000 2nd Offense – Minimum 15 day & $ 1,000 3rd Offense – Minimum 30 day & $ 2,500 3rd Offense – Minimum 30 day & $ 2,500

Eliminates anabolic steroids from racing competition Eliminates anabolic steroids from racing competition Thresholds for FDA-permitted anabolics Thresholds for FDA-permitted anabolics Stanozolol Stanozolol Boldenone (Equipoise) Boldenone (Equipoise) Nandrolone Nandrolone Testosterone Testosterone days withdrawal time days withdrawal time Model Rules Phase 3 (2007) Anabolic Steroids

Model Rule on Anabolic Steroids Contains internationally accepted urinary threshold limits Contains internationally accepted urinary threshold limits Plasma thresholds will be added once the University of Florida administration studies are completed and data is analyzed in early December Plasma thresholds will be added once the University of Florida administration studies are completed and data is analyzed in early December Recommendations for implementation approved by RMTC and RCI in March 2008 Recommendations for implementation approved by RMTC and RCI in March 2008 RMTC, RCI and other industry groups are encouraging every state to complete the adoption process by 12/31 or the first race meet in 2009 RMTC, RCI and other industry groups are encouraging every state to complete the adoption process by 12/31 or the first race meet in 2009

Model Rule on Anabolic Steroids RMTC Board recommends: RMTC Board recommends: –90-day grace period on penalty enforcement when rule is introduced –Notification to owner/trainer for overage –No fine or loss of purse absent aggravating circumstances –After 90 days, jurisdictions should follow the penalty guidelines in the model rules $500 and loss of purse for 1st violation –Pre-entry testing must be made available in some form

Model Rule on Anabolic Steroids RMTC Board recommends: RMTC Board recommends: –Should not be administered within 45 days of a race –If needed outside of 45 days, must be documented by veterinarian, must include diagnosis and be filed with regulatory body –Horse should then test negative before being allowed to enter –Claimed horses may be tested on request and at the cost of claimant. If positive, claim can be voided and testing cost borne by original owner

Language adopted Language in the process of being adopted Process pending completed administration Process has not been started No horse racing or harness racing commission Anabolic Steroid Model Rule Adoption Progress

Standard operating procedures, best practices and uniform testing protocols Standard operating procedures, best practices and uniform testing protocols Quality assurance & blind sample programs Quality assurance & blind sample programs Laboratory accreditation to international standards Laboratory accreditation to international standards Standards for sample collection and frozen samples for future testing as a deterrent Standards for sample collection and frozen samples for future testing as a deterrent National research & reference laboratories National research & reference laboratories Drug Testing Initiative Phase 4 ( )

Research Program Research grants - $965,000 to date –Performance enhancers Erythropoietin, Ethanol and Cone Snail Venom Erythropoietin, Ethanol and Cone Snail Venom –Therapeutics Procaine Penicillin, Flunixin, Clenbuterol and Amicar Procaine Penicillin, Flunixin, Clenbuterol and Amicar –Environmental contaminants Morphine and Cocaine Morphine and Cocaine –Unknowns from backstretch contacts 25-horse research training stable Dr. Don Catlin – Anti-Doping Research Lab

Research Program Developing tests for “designer” drugs Developing tests for “designer” drugs “Unknown” acquisition and analysis: “Unknown” acquisition and analysis: –RMTC works with sources and purchases products being marketed as “performance enhancing” –Over a dozen vials and syringes have been analyzed over the past 2 years –Majority contain over-the-counter products with food coloring and have minimal effect –In 2007, one unknown led to a federal investigation and prosecution of a “race-day medication” website

Withdrawal Times Identify and prioritize drugs with legitimate uses Identify and prioritize drugs with legitimate uses Collect previous studies Collect previous studies If science is insufficient, then perform administrations on a minimum of 20 horses If science is insufficient, then perform administrations on a minimum of 20 horses Research costs of administration, collection and analysis are $20,000-$40,000 depending on drug Research costs of administration, collection and analysis are $20,000-$40,000 depending on drug Plasma is preferred, but will collect both urine and plasma Plasma is preferred, but will collect both urine and plasma Ultimate goal: uniform administration, threshold level and withdrawal time Ultimate goal: uniform administration, threshold level and withdrawal time

Withdrawal Times Research complete on: Research complete on: – –Aminocaproic Acid – –Carbazochrome – –Clenbuterol – –Procaine Penicillin – –Cimetidine – –DMSO – –Flunixin – –Furosemide – –Ketoprofen – –Omeprazole – –Phenylbutazone – –Ranitidine

Withdrawal Times Priority Group 1 Priority Group 1 –Acepromazine –Butorphanol –Detomidine –Glycopyrrolate –Lidocaine –Mepivacaine –Methocarbamol –Pyrilamine Anabolic Steroids Anabolic Steroids –Boldenone –Nandrolone –Stanozolol –Testosterone

Withdrawal Times Database Withdrawal times posted for 18 jurisdictions and over 70 drugs Database is searchable by drug and by jurisdiction Over 10,000 unique users in first year “Withdrawal Times” link on rmtcnet.com

Endorsed NTRA Safety and Integrity Alliance Committed $300,000 over 2 years to support comprehensive review and research for the development of best practices, proper procedures and model rules on the use of corticosteroids Scientific Advisory Committee to design research project for Dantrolene and Fluphenazine, and establish thresholds and withdrawal times Approved proposal to support and fund the continuation of TIP and IDTA programs in 2009 Approved hiring of assistant director Next meeting in conjunction with TRA/HTA meeting and Harness Congress in Las Vegas on February 8 September 2008 Board Meeting

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