This article and any supplementary material should be cited as follows: Riechers RG, Shuster JL, Bryan KJ, Burant C, Ball SL. Prior housing conditions and sleep loss may affect recovery from brain injury in rats: A pilot study. J Rehabil Res Dev. 2013;50(4):455–62. Slideshow Project DOI: /JRRD JSP Prior housing conditions and sleep loss may affect recovery from brain injury in rats: A pilot study Ronald G. Riechers, MD; Jaime L. Shuster, MA; Kathryn J. Bryan, PhD; Christopher Burant, PhD; Sherry L. Ball, PhD
This article and any supplementary material should be cited as follows: Riechers RG, Shuster JL, Bryan KJ, Burant C, Ball SL. Prior housing conditions and sleep loss may affect recovery from brain injury in rats: A pilot study. J Rehabil Res Dev. 2013;50(4):455–62. Slideshow Project DOI: /JRRD JSP Aim – Understand effect of combat-associated conditions such as sleep deprivation (SD) on subsequent traumatic brain injury (TBI). Relevance – Combat operations are associated with high stress and prolonged SD. – TBI is signature injury of conflicts in Iraq and Afghanistan.
This article and any supplementary material should be cited as follows: Riechers RG, Shuster JL, Bryan KJ, Burant C, Ball SL. Prior housing conditions and sleep loss may affect recovery from brain injury in rats: A pilot study. J Rehabil Res Dev. 2013;50(4):455–62. Slideshow Project DOI: /JRRD JSP Method Tested 4 groups of rats: – 24 h of SD in isolation followed by TBI (SD+CCI). – No SD in isolation followed by TBI (no SD+CCI). – Normal housing followed by TBI. – Normal housing and no TBI. Tested rats with beam walk test and adhesive removal test at baseline and 4, 7, and 14 days after TBI.
This article and any supplementary material should be cited as follows: Riechers RG, Shuster JL, Bryan KJ, Burant C, Ball SL. Prior housing conditions and sleep loss may affect recovery from brain injury in rats: A pilot study. J Rehabil Res Dev. 2013;50(4):455–62. Slideshow Project DOI: /JRRD JSP Results SD+CCI group: – Earlier recovery than no SD+CCI group. No SD+CCI group: – Recovered slower than all other groups. Data suggest that: – 24 h of preinjury SD results in faster recovery. – Novel or social isolation conditions impedes recovery.
This article and any supplementary material should be cited as follows: Riechers RG, Shuster JL, Bryan KJ, Burant C, Ball SL. Prior housing conditions and sleep loss may affect recovery from brain injury in rats: A pilot study. J Rehabil Res Dev. 2013;50(4):455–62. Slideshow Project DOI: /JRRD JSP Conclusion Combat environment may contribute to complexities associated with TBIs common in U.S. servicemembers.