Pensamientos sobre FDR Alberto Medina 10 th, Dec. 2012.

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Pensamientos sobre FDR Alberto Medina 10 th, Dec. 2012

FDR. ¿Protein or Peptide?

How we define an experiment?

Missed entries

False positives ¿FDR por Fracción o Experimento?

12 exp. Grouping by experiment

12 exp. Grouping by cell line (3)

Chr16 proteins. NO FDR 388pr/319.

1 exp = 10 searches FDR 1% protein. 292/239 (genes).

1 exp = 1 search (10 exps). FDR 1% protein. 316/260

Sensivity

1 exp = 1 search (10 exps). FDR 1% protein. 316/260

1 exp = 1 search (10 exps). FDR 1% peptide. 336/279