Case 4 F, 70 ys, lower leg Erythematous patch Clinical suspicious: pemphigoid? Patient followed by Department of Oncology.

Slides:

Advertisements

Similar presentations

Case 5 M, 78 ys Violaceous plaque on the penis History of nodal Mantle Cell Lymphoma (courtesy Prof. A. Maiorana)

Advertisements

Research Techniques Made Simple: T-Cell Receptor Gene Rearrangement

Case 6 F, 75 ys Erythematous nodule of the lower left leg.

HCL Patient Seminar September 2014 Quality of Life Monica Else.

Diagnostic Challenge Pathology for Neurosurgery & Neurology Residents Department of Pathology University of Oklahoma Health Sciences Center, Oklahoma City,

MedPix Medical Image Database COW - Case of the Week Case Contributor: Caitlin M Nickens Affiliation: Uniformed Services University.

HANDOUT 2 B-CELL INFILTRATES. CASE 6: ADDITIONAL FINDINGS B-cells negative with antibodies to: CD5 CD10 CD23 BCL-6 cyclin D1.

NOT ALL SWELLING WITH REDNESS AND BAD SMELLY DISACHRGE IS NECESSARLY AN ABSCESS Al-Sharabati, Mohamed Barakat, MD, Pathologist Rasheed, Osaid, RN, CNS.

Clinical case A 18 years old female presented with a 3 years- history of polymorphic skin lesions, at inferior limbs Clinical features Laboratory - an.

Primary Non-Hodgkin's Lymphoma of Bone in Children by Michael P. Glotzbecker, Leslie S. Kersun, John K. Choi, Brian P. Wills, Alyssa A. Schaffer, and John.

Lananh Nguyen, M.D. Division of Neuropathology University of Pittsburgh Medical Center 15-year-old boy presenting with back pain and skull lesion.

Case Study 42 Henry Armah, M.D., M.Phil.. Question 1 Clinical history: 80-year-old male with past medical history of malignant non-Hodgkin’s lymphoma,

Case No. 1 Kunkanit Suntipraron, M.D. Vesarat Wessagowit, M.D., Ph.D.

LyP Three histologic types of LyP have been described: types A, B and C. D ?

Dermatology slide Haitham Bader Ninaveha Medical college.

KCP 797 강남세브란스병원박혜성. 33/M, Cervical lymphadenopathy: R/O TB, R/O nonspecific lymphadenopathy R/O TB, R/O nonspecific lymphadenopathy.

The value of molecular diagnostics in primary cutaneous B-cell lymphomas in the context of clinical findings, histology, and immunohistochemistry Moritz.

Copyright © 2013 American Medical Association. All rights reserved.

Transthoracic needle biopsy of lung adenocarcinoma: all tumour cells are stained with 5A4 clone (anaplastic lymphoma kinase (ALK) immunohistochemistry.

Heparin-induced skin lesions

Hydroa vacciniforme-like cutaneous T-cell lymphoma (CTCL) These patients often have severe insect bite hypersensitivity. The lesions pictured in Fig

Volume 31, Issue 2, Pages (June 2013)

PRIMARY CUTANEOUS γδ T-CELL LYMPHOMA:REPORT OF A RARE ENTITY

CD30+ Cutaneous Anaplastic Large-Cell Lymphoma of the Upper Eyelid: A Case Report - DOI: / Fig. 1. Clinical aspect of a primary cutaneous.

Large-Cell Transformation of Mycosis Fungoides Occurring at the Site of Previously Treated Cutaneous B-Cell Lymphoma Jennifer L. Herrmann, Naveed Sami

Early T-Cell Precursor ALL in 5 Year Old Female

Interleukin-12 Therapy of Cutaneous T-Cell Lymphoma Induces Lesion Regression and Cytotoxic T-Cell Responses by Alain H. Rook, Gary S. Wood, Elisa K. Yoo,

Initial Diagnosis of MF-CTCL: A Collaborative Approach

Oncolytic measles virus in cutaneous T-cell lymphomas mounts antitumor immune responses in vivo and targets interferon-resistant tumor cells by Lucie Heinzerling,

Case Sharing Presentation

Practical Management of CD30+ Lymphoproliferative Disorders

Volume 1, Issue 4, Pages (July 2015)

TNM classification system for primary cutaneous lymphomas other than mycosis fungoides and Sézary syndrome: a proposal of the International Society for.

Volume 4, Issue 2, Pages (March 2018)

Pathologic Diagnosis of Cutaneous Lymphomas

Josh Wharton, MD, David Roffwarg, BS, Jeremiah Miller, MD, Daniel J

Focus on lymphomas Cancer Cell

Volume 4, Issue 4, Pages (May 2018)

Rapid deterioration in a patient with primary aggressive cutaneous epidermotropic CD8+ cytotoxic T-cell (‘Berti’) lymphoma after administration of adalimumab

Volume 3, Issue 6, Pages (November 2017)

Development of a reticular rash in a febrile woman: An unusual cutaneous presentation of angioimmunoblastic T-cell lymphoma Michelle S. Min, MSci, Jonathan.

WHO-EORTC classification for cutaneous lymphomas

The value of molecular diagnostics in primary cutaneous B-cell lymphomas in the context of clinical findings, histology, and immunohistochemistry Moritz.

Serpiginous mycosis fungoides in a 21-year-old man

Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report by Richard L.

Cybele Fishman, MD, Martin C Mihm, MD, Arthur J Sober, MD

Radiation Therapy for Cutaneous T-Cell Lymphomas

Pyoderma gangrenosum in a patient with cutaneous T-cell lymphoma

Treatment of 7 patients with relapsed/refractory NK/T-cell lymphomas treated with pembrolizumab. Treatment of 7 patients with relapsed/refractory NK/T-cell.

Management of refractory early-stage cutaneous T-cell lymphoma (mycosis fungoides) with a combination of oral bexarotene and psoralen plus ultraviolet.

Volume 4, Issue 10, Pages (November 2018)

Case Study 35 Henry Armah, M.D., M.Phil..

Novel Mutations Involving NF-κB and B-Cell Signaling Pathways in Primary Cutaneous Large B-Cell Lymphoma, Leg-Type and Comparison with Sézary Syndrome

Volume 1, Issue 2, Pages (March 2015)

Volume 4, Issue 6, Pages (July 2018)

Volume 5, Issue 2, Pages (February 2019)

Metastastic vulvar squamous cell carcinoma mimicking genital herpes

Hong Wu, Mitchell Smith, Michael M

Large-Cell Transformation of Mycosis Fungoides Occurring at the Site of Previously Treated Cutaneous B-Cell Lymphoma Jennifer L. Herrmann, Naveed Sami

Hovik J. Ashchyan, BA, Katherine K. Brown, MD JAAD Case Reports

Expression of the CD4+ Cell-Specific Chemoattractant Interleukin-16 in Mycosis Fungoides Volker Blaschke, Kristian Reich, Michael Letschert, Florian.

T Cell Receptor-γ Gene Analysis of CD30+ Large Atypical Individual Cells in CD30+ Large Primary Cutaneous T Cell Lymphomas Sylke Gellrich, Anke Wilks,

Histological and immunohistochemical evaluation of primary central nervous system lymphoma. Histological and immunohistochemical evaluation of primary.

Leticia Quintanilla-Fend LYWS-275 (C646-15)

Analysis of PD-L1 tumour-cell membrane staining concordance between PD-L1 immunohistochemistry 22C3 and 28-8 assays across all matched tumour biopsies.

Emilie Doré Badje, MD, Trilok Tejasvi, MD, Alexandra Hristov, MD

CD4/CD8 double-negative early-stage mycosis fungoides associated with primary cutaneous follicular center lymphoma Jeong Hee Cho-Vega, MD, PhD, Jaime.

Rare presentation of disseminated follicular lymphoma as an ill-defined reticular patch over the scalp and forehead Faezeh Talebi-Liasi, MD, Sophia Sandhu,

A: Lesion showing diffuse aggregates of large histiocytoid cells with abundant cytoplasm that admixed with lymphocytes, plasma cells, and neutrophils (hematoxylin.

Skin punch biopsy from an upper back lesion showing extensive dermal neutrophilic infiltrate consistent with diagnosis of Sweet's syndrome. Skin punch.

Presentation transcript:

Case 4 F, 70 ys, lower leg Erythematous patch Clinical suspicious: pemphigoid? Patient followed by Department of Oncology

Punch biopsy

CD20

CD3

CD79a

CD5

CD23

CD43

Mib-1

Further clinical information  History of B-CLL FINAL DIAGNOSIS FINAL DIAGNOSIS Cutaneous localization of B-CLL Cutaneous localization of B-CLL CD20+; CD79a+; CD5+; CD23+; CD43+; CD3-. CD20+; CD79a+; CD5+; CD23+; CD43+; CD3-.

Follow-up: spontaneous resolution of the lesion (Kazakov D et al. Dermatology 2003; 207: )  H&E: monomorphous lymphocytes, small size but with hyperchromatic nuclei  Immunohistochemistry: large panel r/o Mantle Cell Lymphoma (cyclin D1-; low Mib-1) r/o Mantle Cell Lymphoma (cyclin D1-; low Mib-1)  Clinical information: not given, at least directly!