Nucleic Acids nucleic acids store and transmit hereditary information Contain the following elements: C, H, N, O, P Two types of nucleic acids: DNA RNA
1. DNA = Deoxyribonucleic acid “encodes the instructions”(genetic code) for the specific amino acid sequence of a protein is copied and passed from one generation of cells to another (condensed DNA = chromosome) Eukaryotes- nucleus Prokaryotes- cytoplasm
2. RNA = Ribonucleic acid functions in the actual synthesis of proteins coded for by DNA mRNA
DNA ==> RNA ==> Protein mRNA carries the encoded information to the ribosomes; tRNA carries the amino acids to the ribosome; & rRNA is a major component of ribosomes DNA ==> RNA ==> Protein
Structure of Nucleic Acids Nucleic acids are macromolecules built of monomers called NUCLEOTIDES
Each nucleotide consists of: 1. 5-carbon sugar: -deoxyribose in DNA -ribose in RNA 2. Phosphate group (attached to #5 carbon on sugar) 3. Nitrogenous base purines (double ring; A & G) pyrimidines (single ring; C, T & U)
nucleotides are joined together by phosphodiester linkages (between phosphate of one nucleotide and the sugar of the next) this results in a backbone with a repeating pattern of: sugar-phosphate-sugar-phosphate... 7
Dehydration Synthesis