Topic 7 Nucleic Acids and Proteins
DNA Structure
DNA Structure cont’d
DNA Replication
Organization of DNA in Eukaryotes Replication Initiation Sites Where the replication of DNA begins (may also be known as O.O.R.)
Nucleosomes Globular structures that contain 8 histone proteins, with DNA wrapped around 2 times Are connected to other nucleosomes by another histone protein (H1), known as a linker Essential for packaging DNA for mitosis/meiosis Involved in gene regulation
DNA Folding
Repetitive Sequences Repetitive base sequences that are not translated Sometimes called satellite DNA Sequences between bp May be repeated as much as 10,000x Constitute 10-40% of euk. genomes Function unknown A vey small portion of euk. DNA is single copy/unique genes
Introns and Exons