By: Little6CB18 and Little6CC3 Klinefelter Syndrome By: Little6CB18 and Little6CC3

What is Klinefelter Syndrome? Klinefelter syndrome is a genetic disorder that affects males. A male is born with one or more extra X chromosomes. Males that don’t have Klinefelter syndrome have one X and one Y chromosome. Klinefelter syndrome is also known as XXY syndrome.

How does a person inherit Klinefelter syndrome? Klinefelter syndrome cannot be inherited. During the reproductive process, when a reproductive cell has too many chromosomes, it results in Klinefelter syndrome. Klinefelter syndrome is recessive.

What are the chances of a male having Klinefelter syndrome passing it to their offspring? Klinefelter syndrome cannot be passed to their offspring. Klinefelter syndrome is when a male is sterile which means it cannot reproduce children.

How prevalent is Klinefelter syndrome? How is Klinefelter syndrome diagnosed? Before birth through amniocentesis. In childhood when a male is going through puberty. Adulthood through chromosome tests and medical history. Klinefelter syndrome occurs in 1 in 500 to 1,000 males. Klinefelter syndrome does not occur in females.

Symptoms of Klinefelter Syndrome Underdeveloped Muscles Tiredness Early heart disease Change body shape Reduced facial hair Delayed puberty Infertility Taller than other males with long legs and wide hips Breast development

Life Expectancy Treatment The life expectancy of a male with Klinefelter syndrome is normal. There is no treatment available for Klinefelter syndrome. There is treatment to fix the testosterone levels. Klinefelter syndrome individuals can get help with language and learning problems.

Possible Genotypes of Parents There are no genotypes of parents because those with this disease are infertile. If a child is born with this disease, its parents can have any genotypes.

Everyday Life with Klinefelter Syndrome Males with Klinefelter syndrome live an average life.

What limitations does a male have with Klinefelter syndrome? A male with Klinefelter syndrome will not have any limitations but may not be able to produce children. They can look into infertility or adoption if needed. What are some organizations that can help a family cope with Klinefelter syndrome? There are not any organizations to help families cope with Klinefelter syndrome since it only makes a male have an extra chromosome.

Is there a possible cure for Klinefelter syndrome? There is no cure for Klinefelter syndrome. There are cures for the symptoms of Klinefelter syndrome.

Bibliography http://ghr.nlm.nih.gov/condition=klinefeltersyndrome http://images1.clinicaltools.com/images/gene/trisomyxxy.jpg (picture on symptoms page) http://www.mamashealth.com/syndrome/Kleinfeltr.asp http://www.dundee.ac.uk/medther/tayendoweb/images/klinefelters.htm http://www.peacehealth.org/kbase/topic/mini/hw183686/overview.htm http://www.healthofchildren.com/images/gech_0001_0002_0_img0156.jpg (picture of different types of chromosomes on limitations/ organizations page) http://www.3dscience.com/img/Products/3D_Models/Human_Anatomy/Collections/Male_Collection/Zygote-3D-Male-Human-Anatomy-Collection-3.jpg (picture of male on chances of passing Klinefelter syndrome to their offspring) Picture of man on everyday life page is from clip art on my computer) http://graphics8.nytimes.com/images/2004/08/31/science/0831-sci-sub-BRODYch.jpg (picture on cover page) http://img.tfd.com/mosbycam/thumbs/500227-fx55.gif (picture on possible cure page) http://home.earthlink.net/~heinabilene/karyotypes/49XXXXY.jpg (picture on possible genotypes page)