Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.

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Presentation transcript:

Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465

Recycle 6 times without any apparent loss of activity

Montmorillonite KSF clay catalyzed one-pot synthesis of a-aminonitriles Tetrahedron 60 (2004) 1767–1771

solid acids recycle % % %

Nickel(II) chloride catalyzed one-pot synthesis of - aminonitriles Journal of Molecular Catalysis A: Chemical 225 (2005) 169–171

Gallium (III) triflate catalyzed efficient Strecker reaction of ketones and their fluorinated analogs PNAS March 6, 2007 vol. 104 no. 10

Fe(Cp) 2 PF 6 catalyzed efficient Strecker reactions of ketones and aldehydes under solvent-free conditions Tetrahedron Letters 49 (2008) 640–644

1 : 1 : 1.3