Chapter 15: Signal Transduction

OUTLINE 15.1 From Extracellular Signal to Cellular Response 15.2 Studying Cell-Surface Receptors 15.3 Highly Conserved Components of Intracellular Signal-Transduction Pathways 15.4 General Elements of G Protein-Coupled Receptor Systems 15.5 G Protein-Coupled Receptors That Regulate Ion Channels 15.6 G Protein-Coupled Receptors That Activate or Inhibit Adenylyl Cyclase 15.7 G Protein-Coupled Receptors That Activate Phospholipase C

FIGURE 15-1 General principles of signaling by cell-surface

FIGURE 15-2 General schemes of intracellular signaling 15.1 From Extracellular Signal to Cellular Response Signaling Molecules Can Act Locally or at a Distance

FIGURE 15-2(a) General schemes of intracellular signaling

FIGURE 15-2(b) General schemes of intracellular signaling

FIGURE 15-2(c) General schemes of intracellular signaling

FIGURE 15-2(d) General schemes of intracellular signaling

Extracellular Signal

Second Messengers

Reporter Constructs