CAREERS FROM BIOLOGY IMAGES

A lesion in human cervical epithelium infected with human papilloma virus (HPV16). Early viral proteins (green) bind to and reorganise the keratin filaments (red) towards the edge of the cell. Cell nuclei are stained with DAPI (blue). This image was featured on the back of ‘Big Picture: Careers From Biology’, and the case study it relates to is Gift Nambela, whose work involves running assays to detect human papilloma virus. Credit: MRC NIMR, Wellcome Images. Human egg HPV in cervical epithelium

A scientist studying a sequence of DNA looking for alignment of the sequence relating to the Lipl32 gene, which is present among pathogenic leptospires (a genus of Gram-negative bacteria). The alignment was performed to find a consensus sequence that could be used to generate a set of DNA primers and a probe to be used in a real-time PCR assay. This assay will allow scientists to target the specific DNA sequence to detect the presence of this DNA sequence, and thus pathogenic leptospires, in urine. Credit: Pablo Rojas, Wellcome Images. BIGPICTUREEDUCATION.COM Secondary oocyte during in vitro fertilisation Scientist studying DNA sequence data

BIGPICTUREEDUCATION.COM Osteoarthritis of patello-femoral joint X-ray, lateral (side view) of a knee in extension, showing osteoarthritis of the joint with diminution of the joint space and lipping. Credit: Wellcome Photo Library, Wellcome Images.

A model of the skeleton of the hand suggesting inflammatory conditions such as rheumatoid arthritis or conditions affecting the ulnar nerve. Credit: N Seery, Wellcome Images. BIGPICTUREEDUCATION.COM Inflammation of the finger

Health visitors leaflet This healthcare leaflet, ‘What is a Health Visitor?’, was produced by Sterling Health. Credit: Wellcome Library, London.. BIGPICTUREEDUCATION.COM

This image shows a computed tomography (CT) scan of a human chest. Credit: Wellcome Images, Wellcome Images. BIGPICTUREEDUCATION.COM CT scan

This example of functional magnetic resonance imaging (fMRI) shows the visual cortex in yellow at the back of the brain. This is a cut-away section at the level of the eyes (transverse and sagittal). Credit: Mark Lythgoe and Chloe Hutton, Wellcome Images. BIGPICTUREEDUCATION.COM Cut-away fMRI scan

A digital illustration showing a young woman and a man in a white suit, possibly a pharmacist, in a pharmacy. The overlay shows arrows, cigarettes (one with a cross though it) and a stop sign. Credit: Alex Williamson, Wellcome Images. BIGPICTUREEDUCATION.COM Smoking cessation advice

A cut-away model of the human immunodeficiency virus (HIV), the cause of AIDS. Credit: John Wildgoose, Wellcome Images. BIGPICTUREEDUCATION.COM Model of HIV

Environmental management This canal was built around an urban settlement in the Middle East so the rodent reservoir hosts of Leishmania would not be able to swim over and reinvade an area where the rodent population had previously been controlled. Credit: Wellcome Images, Wellcome Images. BIGPICTUREEDUCATION.COM

Medical waste This biohazard symbol is often used to warn of a potential biological hazard. This could be an organism or a substance derived from an organism and might include medical waste or samples of a microorganism, virus or toxin. Credit: Wellcome Library, London. BIGPICTUREEDUCATION.COM

Humulus lupulus, or ‘hops’ A herbaceous climbing plant with coarse-toothed leaves and ‘hop’ flower heads. The cone-like flowers are traditionally used in beer brewing for their distinctive, bitter flavour. The young shoots have also been eaten as a vegetable, rather like asparagus. Extracts containing lupulin have also been used as a galactagogue (to increase the flow of milk in nursing mothers). Credit: Rowan McOnegal, Wellcome Images. BIGPICTUREEDUCATION.COM

Reusing our images Images and illustrations All images, unless otherwise indicated, are from Wellcome Images. Contemporary images are free to use for educational purposes (they have a Creative Commons Attribution, Non-commercial, No derivatives licence). Please make sure you credit them as we have done on the site; the format is ‘Creator’s name, Wellcome Images’.Creative Commons Attribution, Non-commercial, No derivatives licence Historical images have a Creative Commons Attribution 4.0 licence: they’re free to use in any way as long as they’re credited to ‘Wellcome Library, London’.Creative Commons Attribution 4.0 licence Flickr images that we have used have a Creative Commons Attribution 4.0 licence, meaning we – and you – are free to use in any way as long as the original owner is credited.Creative Commons Attribution 4.0 licence Cartoon illustrations are © Glen McBeth. We commission Glen to produce these illustrations for ‘Big Picture’. He is happy for teachers and students to use his illustrations in a classroom setting, but for other uses, permission must be sought. We source other images from photo libraries such as Science Photo Library, Corbis and iStock and will acknowledge in an image’s credit if this is the case. We do not hold the rights to these images, so if you would like to reproduce them, you will need to contact the photo library directly. If you’re unsure about whether you can use or republish a piece of content, just get in touch with us at