Global Alignment and Collaboration Jo

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Presentation transcript:

Global Alignment and Collaboration Jo

About EMBL-EBI Part of the European Molecular Biology Laboratory International, non-profit research institute Europe’s hub for biological data services and research

Science is global

2. Discoverability through structured data structured data is one of the true enablers of life science -Discovery of homology between genes across species -Predicting function based on protein folds Structured data can be cross-analysed, compared by algorithm, and encourages development of new products and tools

Osteoarthritis

Data Ecosystem Unstructured/ semi- structured Structured Added Value Literature Ontologies Metadata Ontologies Metadata Citations & Links ORCIDs DOIs, ROIs PIDs Algorithms Text and data mining Analytical tools

A stable, freely available, shared repository Europe PMC Abstracts: 30 million Full-text articles: 3 million Article citation counts Grants ORCIDs Semantic annotation Data citations Data integration Europe PMC is a member of the PMC International Collaboration. Supports OA mandates of 26 European funders of life science research

Europe PMC content

The scent of information It's healthy to remember that users are selfish, lazy, and ruthless in applying their cost-benefit analyses Information Foraging: by JAKOB NIELSEN, June 30, Data placement: where people will find it Scent alone is not scientific … “retaining files and being prepared to share them” ≠ accessible data

Data Citation Principles Data as legitimate, citable products of research Attribution and credit Cited as evidence for a claim Unique identification Access Persistence Specificity and verifiability (provenance) Interoperability and flexibility

BioStudy EBI BioStudies database for unstructured data Study Publications Ontologies Data files Other DBs Metadata Other DBs

PIDs build infrastructure for scientific discovery and credit systems Reused from: seier+seier, Flickr Reused from: Images Money, Flickr

(1) Europe PMC and Use of the claiming tool ~400K article claims ~ 21K unique ORCIDs Incorporation into Europe PMC 1.2M unique articles in Europe PMC linked to ORCIDs (cf. PubMed 12K) An integrated encyclopedia of DNA elements in the human genome. (PMID: PMCID:PMC )

A network of repositories

Cross Disciplinary Integration

Elixir: An international distributed infrastructure for Data Standards Tools Compute Training Industry Alignment with BD2K (NIH)