GLENN CHENEY Senior Manager Technical Communication Pharmanex R&D

Weight Management

Daily Activity 12 3 COMPONENTS

EAT ONE HEALTHY MEAL F&V – Correlation between F&V consumption and body composition PROTEIN – for satiety and muscle tone COMPLEX CARBS – affects rate of energy absorption FAT – For satiety DAIRY – correlation between dairy consumption and body composition (also protect against calcium loss) Vegetables Fruits Protein Fat Dairy Complex Carbs

REPLACE TWO MEALS WITH AC SHAKES

EFFECT OF A SPECIAL FIBER IN AC SHAKES Without unique fiber

EFFECT OF A SPECIAL FIBER IN AC SHAKES Without unique fiber Effect of special fiber in AC Shakes Unique fiber blend promotes fullness Balance blood sugar ↓ cravings, so you consume fewer calories

REPLACE TWO MEALS WITH AC SHAKES THREE SNACKS A DAY nuts ½ apple + 2 tsp PB

Healthy Eating 123

123 Daily Activity 5 ─7× Per Week Ultimate Goal: 1 Hour per day – Break it up into 10 min increments – 10 min × 6 per day = 60 mins – Gradually build up to 60 mins Don’t pick activities you dislike – Play Wii Sports / “Just Dance” with your kids Be accountable to yourself & others

Healthy Eating 123 Daily Activity

PROVEN INGREDIENTS; THE RIGHT DOSE Garcinia cambogia fruit extract Gymnema sylvestre extract Chromium Forskohlii extract Lagerstroemia speciosa Fenugreek fiber 4,700 mg 400 mg 400 mcg 425 mg 48 mg 2,000 mg EQUIVALENT TO 20 CAPSULES! Total 7,575 mg

AC COMPLEX AND AC SHAKES TOGETHER: + = 100% Clinically Effective Dose

Wang H, et al. Effects of catechin enriched GT on body composition. Obesity Apr;18(4): Green Tea improves Body Composition 90 days; subjects received Green Tea catechins ↓ intra-abdominal fat (IAF) by 5.6 cm 2 ↓ in waist circumference 90 Day RCT of Green Tea Auvichayapat et al. Effectiveness of green tea on weight reduction in obese Thais: A randomized, controlled trial. Physiol Behav Feb 27;93(3): Week 8: Week 12: No difference in food intake, or physical activity Δ in resting energy expenditure = kJ/day (p < 0.001) Stress response* significantly ↓ (p < 0.05) *VMA 60 subjects: BMI > 25 GREEN TEA STUDIES

EFFECTS OF STRESS ON APPETITE High Cortisol Individuals: – Consumed more calories – Ate significantly more sweet foods – More negative moods Dietary Restraint = consciously trying to limit food intake to maintain a desired body weight HIGH DIETARY RESTRAINT IS ASSOCIATED WITH HIGH CORTISOL 1. Epel ES, et al. Psychoneuroendocrinology 2001;26: McLean JA, Barr SI, Prior JC. Am J Clin Nutr 2001;73:7-12.

AGELOC VITALITY IMPROVES PHYSICAL ENDURANCE Week 0 Time to Exhaustion Treadmill (min) Control ageLOC Vitality Week Week %

AGELOC VITALITY PRESERVED 57% MUSCLE GLYCOGEN COMPARED TO NON-TREATMENT GROUP Muscle glycogen (mg/g wet wt.) Non-Exercise Control Results from a pre-clinical study in mice with ageLOC Vitality Blend. Ferguson et al. Targeting Mitochondria 2010 Berlin, Germany November 18-19, Exercise mg/g (-30 % ) Exercise w/ ageLOC Vitality 0.25 mg/g (-13 % )

AGELOC VITALITY INGREDIENT PROMOTES FAT METABOLISM DURING PROLONGED EXERCISE Pharmanex ingredient study by Fit Stop Human Performance Laboratory Medicine and Science in Sports and Exercise 2001; 33(5) Supplement 1:pg S Exercise Time (minutes) Fat burning Zone Carbohydrate Burning Zone Includes: glucose and glycogen Respiratory Exchange Ratio (RER) Before an ageLOC Vitality ingredient After 6 weeks of an ageLOC Vitality ingredient

Daily Activity 123

= = WEIGHT MANAGEMENT SUCCESS