Educating Tomorrow's Technology Leaders for Career Success MEDICAL SCHOOL CAMPUS Neuroprosthetics Research Group Director: Dr. Sanchez, Co-director: Dr. Prasad Rosenstiel Room RSMB-4080, Medical Campus Joint Bioengineering and Endourology Laboratory, Co-Director: Dr. Salas, Co-director: Dr. Leveillee Miller School of Medicine, 1400 NW 10 th Ave, Suite 509 Tissue Engineering Laboratory, Director: Dr. Stabler Miller School of Medicine, Diabetes Research institute Sensory Neurophysiology Laboratory Director Dr. Rajguru Miller School of Medicine, Ear Institute Physiomimetic Microsystems Laboratory Director: Dr. Agarwal Miller School of Medicine, BioNIUM, Pathology DUAL LABORATORIES (Coral Gables and Medical Campuses) Biomaterials Laboratory, Director: Dr. Andreopoulos McArthur Engineering Building, Room MEB 144B Rosenstiel Room RSMB-8075A, Medical Campus Cartilage Tissue Engineering and Mesenchymal Stem Cells Laboratory, Director: Dr. Cheung McArthur Engineering Building, Room MEA 168 Miami VA Medical Center, Research Building Biomedical Optics Laboratory, Director: Dr. Manns, Co-director: Dr. Parel Mc Arthur Engineering Annex, Room MEA 170B Bascom Palmer Eye Institute, Miller Medical School CORAL GABLES CAMPUS Biomedical Atomic Force Microscopy Laboratory, Director: Dr. Ziebarth Mc Arthur Engineering Annex, Room MEA 170A Stem Cell and Mechanobiology Laboratory, Director: Dr. Huang, McArthur Engineering Annex, Room MEA 168 Orthopaedics Biomechanics Laboratory, Director: Dr. Jackson McArthur Engineering Annex, Room MEA 169 Neurosensory Engineering Laboratory, Director: Dr. Ozdamar, Co-director: Dr. Bohorquez McArthur Engineering Building, Room MEB 153 Biomedical Imaging Laboratory, Director: Dr. Zhao McArthur Engineering Annex, Room MEA 201A Scanning Electron Microscopy Laboratory (CoE), Director: Dr. Dauer McArthur Engineering Annex, Room MEA 201B Biomedical Design Laboratory Director: Dr. Montero McArthur Engineering Building, Room MEA 201A BME, Biomedical Engineering Dr. Ozdamar, Chair

Educating Tomorrow's Technology Leaders for Career Success Neuroprosthetics Research Group Dr. Sanchez and Dr. Prasad Neural Electrode Failure Analysis Computational Neural Decoding Clinical Trials in Spinal Cord Injury Brain-Computer Interface Controlled Functional Electrical Stimulation in Spinal Cord Injury EEG Neural Activations in Spinal Cord Injury Spinal Cord Computer Interface

Educating Tomorrow's Technology Leaders for Career Success Dental Stem Cells SSEA4 Tra-1-60 Nestin Sox2 Oct4 Nanog Chondrogenesis TGF-  1- -  1+ Collagen IIAggrecan Stem cells: chondrogenesis of adult stem cells, charaterization of dental stem cells, development of novel bioreactor technology Mechanobiology: mechanobiology of intervertebral disc and stem cells, impact injury of articular cartilage, mechanobiological model of soft tissue Drop tower for impact loading Compression bioreactor After impact injury Subjected to mechanical loading after impact injury Control Human knee articular cartilage Stem Cell and Mechanobiology Laboratory Director: C.-Y. Charles Huang, Ph.D.

Educating Tomorrow's Technology Leaders for Career Success Sensory Neurophysiology Lab – Dr. Suhrud Rajguru Optical Neural Stimulation for basic science and neuroprosthetic applications Auditory and vestibular electrophysiology (above) and eye movements evoked by Infrared radiation of vestibular Neuriepithelium (side) Improving diagnosis and treatment of inner ear disorders Mechanisms of Neuroprotection

Educating Tomorrow's Technology Leaders for Career Success nano macro 10 µm 1 mm 10 cm CELLULAR BIOMECHANICS Physiomimetic Microsystems Laboratory Ashutosh Agarwal, PhD ( Engineering ToolsResearch Projects HEART ON A CHIP CARDIAC PATCHES

Educating Tomorrow's Technology Leaders for Career Success Biomedical Engineering 2014 Dr. Ozdamar, Chair SupervisorSelected Project Titles Dr. Weizhao Zhao Medical Imaging 1. A-Mode Ultrasound for Image-guided surgery by computerized robot and general ultrasound application 2. MRI instrument and MRI image analysis for experimental neuroscience projects Dr. Alicia Jackson Orthopedic Biomechanics 1.Determination of Environmental Effects on Intervertebral Disc Cells 2.Measurement of Transport Properties of Orthopaedic Tissues Dr. Ashutosh Agarwal Biomimetics 1. Biomimetic Neuro-Muscular Junctions 2. Engineered Hydrogels for Stem Cell Culture Dr. Abhishek Prasad (Dr. Justin Sanchez) Neuromotor Engineering 1. Brain-Machine Interface Research 2. Neural-Electrode Interfaces 3. Wireless, Implantable Neural Recording Devices. Dr. Charles Huang Mechanobiology Engr. 1. Cartilage tissue engineering and energy metabolism of intervertebral disc cells 2. Impact injury of articular cartilage Dr. Herman Cheung Stem Cell Engineering 1. The role of mechanic force on the differentiation of human adult stem cells into cartilage, bone and cardiomyocytes 2. Transplantation of adult stem cells to relieve pain caused by diabetic neuropathy in animal model 3. The effect of Vitamin D3 and HGF in bone differentiation in human mesenchymal stem cells Dr. Fabrice Manns Biooptics and lasers 1. Optics of the eye and vision correction (LASIK, presbyopia, intraocular lenses) 2. Ophthalmic surgical and diagnostic devices (aberrometry, optical coherence tomography) Dr. Ray Montero Medical Device Design 1. 3D medical device prototyping 2. Scaffold design for tissue engineering Dr. Noel Ziebarth Tissue Structure / Function 1. Ocular biomechanics assessed through Indentation Testing 2. Solute diffusion in the lens in the lens via fluorescent recovery after photobleaching Dr. Ozcan Ozdamar Neurosensory Engineering 1. Auditory and visual electrophysiological monitoring (with Dr. Bohorquez) 2. Otoacoustic emission measurement system for hearing loss determination (with Drs. Bennett and Bohorquez) Dr. Jorge Bohorquez Medical Instrumentation 1. Anesthesia monitoring for awareness (with Drs. McNeer and Ozdamar) 2. Retinal stress testing system (with Drs. Porciatti and Ozdamar) Dr. Fotios Andreopoulos Biomaterials 1. Growth factor immobilization on 3-D scaffolds 2. Fabrication of electrospun scaffolds with defined architectures Dr. Cherie Stabler Tissue Engineering 1. Macroporous scaffolds and nano-scale coatings for islet transplantation 2. Oxygen generating biomaterials for cellular transplantation Dr. Suhrud Rajguru Sensory Neurophysiology 1. Infrared Neural Stimulation for basic science and neuroprosthetic applications 2. Improving diagnosis and treatment of inner ear disorders