KEY CONCEPT Blood is a complex tissue that transports materials.

Blood is composed mainly of cells, cell fragments, and plasma. Whole blood is made up of different materials. plasma red blood cells white blood cells platelets red blood cells, white blood cells, and platelets plasma

Plasma is a key factor in maintaining homeostasis. molecules diffuse into and out of plasma contains proteins that stabilize blood volume contains clotting factors contains immune proteins

Platelets and different types of blood cells have different functions. The bone marrow manufactures most of the blood components. red blood cell platelet white blood cell

Red blood cells (erythrocytes) make up 40-45 % of all blood cells. transport oxygen to cells and carry away carbon dioxide have no nuclei and contain hemoglobin Hemoglobin is a protein that contains iron to which the oxygen binds

White blood cells (leukocytes) fight pathogens and destroy foreign matter. red blood cell platelet white blood cell

Platelets help form clots that control bleeding. fibrin red blood cell white blood cell

Protein markers define blood types and Rh factors. ABO blood group the most common Rh factor can be negative or positive blood types must be compatible for transfusions Agglutination occurs when blood cells clump together This would occur if someone with Type A blood is given a transfusion from someone with Type B blood. The b antibodies in the Type A blood will attack the B antigens in the Type B blood.

Protein on RBC (antigen) Antibodies in blood plasma Can Donate to Blood Type Genotype Protein on RBC (antigen) Antibodies in blood plasma Can Donate to Can Receive from A IAIA or IAi B IBIB or IBi AB IAIB O ii Rh Factor Rh+ Rh+Rh+ or Rh+Rh- Rh- Rh-Rh-

The lymphatic system collects fluid that leaks out of the capillaries. Lymph is collected from tissues and returned to the circulatory system. heart lymph nodes lymph vessels The lymphatic system collects fluid that leaks out of the capillaries. Lymph vessels have valves to prevent backflow. Lymph nodes filter the lymph and destroy foreign matter. Lymph vessels return cleaned fluid to the circulatory system. If lymph vessels or nodes are damaged, lymph collects in an area.

The lymphatic system is a major part of the immune system. tonsils thymus spleen Structures in the lymphatic system help fight disease. tonsils filter bacteria and viruses thymus develops white blood cells spleen filters lymph, contains immune cells Lymphocytes help destroy pathogens, parasites, and foreign matter.