Repair and Regeneration of the Nervous System. What’s Capable of Being Repaired or Regenerated? Whole Neurons Axons Synaptic clefts Neuromuscular junction.

Slides:



Advertisements
Similar presentations
SYNAPSES AND DRUGS.
Advertisements

Lecture packet 9 Reading: Chapter 7
Development of Neural Circuits Lecture 4. Stages of Cellular Activity n 6 distinct stages 1. Neurogenesis 2. Cell migration 3. Differentiation 4. Synaptogenesis.
Unit V: Movement Muscle Contraction - Part I
SEHS Topic 4.1 Neuromuscular Function
ARMS interacts with  -syntrophin: implications for EphA4 signaling at the neuromuscular synapse Yu CHEN Department of Biochemistry Hong Kong University.
Synapse Formation I April 18, 2007 Mu-ming Poo 1.Steps in the formation of neuromuscular junction 2.Early events of synaptogenesis 3.ACh receptor aggregation.
Axon Guidance How does an axon find the right target?
Synapse formation (2) Effect of postsynaptic cell on presynaptic differentiation –Retrograde signals involved in active zone formation –Synapse elimination.
Principles of Axon Guidance Chemoaffinity Hypothesis – the specificity of wiring is based on recognition of chemical cues Axons reach their targets in.
The Nervous System Medical Biology Mission Hills High School.
Nervous System Communication. Kid Concussions In The News.
Neurons and Action Potential. Objectives 1.Understand the anatomy of a neuron and how signals travel along neurons. Describe parts and function of neuron.
Nerve Regeneration Overview I Mature neurons do not divide to replace injured cells. If injury occurs close to the cell body or the damage is severe, the.
Structure of the nervous system
Chapter 8c Neurons: Cellular and Network Properties.
The Nervous System Medical Biology Mission Hills High School.
PowerPoint Lecture Outlines to accompany
THE NERVOUS SYSTEM. Brain WHAT PARTS DO YOU KNOW THAT ARE IN THE NERVOUS SYSTEM? Spinal Cord Peripheral Nerves.
Neuromuscular Junction (NMJ). Neuromuscular junction Neuromuscular junction : the synapse between motor neuron and muscle fibre Motor neurons : are the.
See also the NOTE GUIDES posted online on the wiki, the online self-quizzes posted on the wiki, and USG pages 6 to 10. Main Content: 1. Sodium Potassium.
Synapse formation completes the wiring of the nervous system Birth and differentiation of neurons Extension of axons/axon guidance Target recognition Synaptic.
Nervous System: General Principles PA 544 Clinical Anatomy Tony Serino. Ph.D.
Basics of the Nervous System
Copyright © 2009 Pearson Education, Inc. Neurons and Neurological Cells: The Cells of the Nervous System  The nervous system  Integrates and coordinates.
 Found around the segments of myelin sheath.  They form the myelin sheath by rotating several times around the axon.  Thus forming a series of rings.
The Nervous System & its Cells. Central (inside skull & spine) Brain Spinal Cord Divisions of the Nervous System Peripheral (outside skull & spine) Nerves.
Development of Neural Circuits Lesson 5. Stages of Cellular Activity n 6 distinct stages 1. Neurogenesis 2. Cell migration 3. Differentiation 4. Synaptogenesis.
1 Psychology 304: Brain and Behaviour Lecture 20.
Chapter 2: Brain Development
Neurons and Neurotransmitters. Nervous System –Central nervous system (CNS): Brain Spinal cord –Peripheral nervous system (PNS): Sensory neurons Motor.
Lecture 2 Neurons, Muscles and Motor Units. Voluntary movement begins.... Brain Spinal cord Motor nerves Muscles.
The Brain and Nervous System Chapter 2. Copyright © 2011 Pearson Education, Inc. All rights reserved. Overview of Nervous System Nervous System - an extensive.
Nervous Tissue: Neuroglia = Support Cells Support cells in the Central Nervous System (CNS) are grouped together as neuroglia Neuroglia literally means.
Unit 3: Biological Bases of Behavior 3-A (The Neuron) Mr. Debes A.P. Psychology.
Read page on drugs and the brain What 3 major concepts should we study to understand this article further?
The Nervous System. iction/drugs/mouse.html.
A.1 Neural Development.
SITES OF SYNAPTIC COMMUNICATION SYNAPSES Created by The North Carolina School of Science and Math.The North Carolina School of Science and Math Copyright.
 Identify the principle parts of the nervous system  Describe the cells that make up the nervous system  Describe what starts and stops a nerve impulse.
Objectives 31.1 The Neuron -Identify the functions of the nervous system. -Describe the function of neurons. -Describe how a nerve impulse is transmitted.
Synapse: Is a junction where a axon interacts with another neuron Presynaptic Terminal: End of the axon Postsynaptic Membrane: Membrane of the dendrite.
PowerPoint ® Lecture Slides prepared by Janice Meeking, Mount Royal College C H A P T E R Copyright © 2010 Pearson Education, Inc. 11 Fundamentals of the.
NERVOUS SYSTEM Objectives: 1. Describe the divisions of the nervous system & basic functioning 2. Explain how information flows through the nervous system.
Nerve Supply to a Muscle. Nerve Supply Motor Neuron: Nerve that stimulates a muscle cell. A single nerve (motor neuron) will supply approximately 150.
Figure 23.1 Growth cones guide axons in the developing nervous system.
A.1 Neural Development IB Biology The basics: The Nervous System
The Synapse A synapse is the functional connection between a neuron and a second cell. The second cell is also a neuron in CNS. In the PNS, the second.
The Synapse and Synaptic Transmission
Synapse formation completes the wiring of the nervous system
Neurons, Synapses and Signaling
Axon Guidance How does an axon find the right target?
ONTOGENETIC DEVELOPMENT OF THE NERVOUS SYSTEM
Early brain development part two
9 Muscles and Muscle Tissue: Part B.
The Nervous System.
NEURAL CONTROL AND COORDINATION
Principles of Axon Guidance
Ms. Scribner’s Biology class
Chloe Henry, Delina Tsegay
SYNAPSES AND DRUGS.
SYNAPSES AND DRUGS.
Schwann cells: Dynamic roles at the neuromuscular junction
The Nervous System.
SYNAPSES AND DRUGS.
Chloe Henry, Delina Tsegay
Synapses occur at the junctions
THE NERVOUS SYSTEM II pp
Presentation transcript:

Repair and Regeneration of the Nervous System

What’s Capable of Being Repaired or Regenerated? Whole Neurons Axons Synaptic clefts Neuromuscular junction Receptors

Whole Neurons Death is programmed (apotosis) or immediated (necrosis)

If you had too much MSG…..

Axons (Peripheral Nerves)

Axons Derive From Growth Cones

How Do Axons Know Where To Go? Blueprint Hypothesis –Axons migrate towards a tissue in a pre- determined manner Chemical Affinity Hypotheis –Axons migrate towards a tissue based on feedback from “chemoattractants” and “chemorepellants” –Ephrin (retractant), Semaphorins (both)

Signaling Disruption of Axon Growth

Synaptic Clefts (Neuromuscular Junction) Principles of Neural Science (Kandel); Chapter 55

Formation of a Neuromuscular Junction Growth cone approaches a new formed myotube Forms an unspecialized contact Multiple axons converge on a single site All but one are eliminated –Survival of the fittest Principles of Neural Science (Kandel); Chapter 55

What Happens With a Loss of Nerve and Tissue? Principles of Neural Science (Kandel); Chapter 55

Differentiation of Synaptic vs. Non- synaptic Regions Principles of Neural Science (Kandel); Chapter 55

Receptor Aggregation Neuregulin: enables the formation of AcH receptors at the neuromuscular junction

Cytoplasmic Proteins link receptors together

Macromolecular Complexes Principles of Neural Science (Kandel); Chapter 55 link pre- and post-synaptic membranes together

Neurotrophic Factors Guide neuron survival and outgrowth on neurons BDNF, NT-3, NT-4 and 5 Hot factor to study beyond neuron repair and regeneration (drug addiction)

Case Study: Stroke, Chemical Warfare, and Neuregulin

Spinal Cord Regeneration with Channel Rhodopsin Achieved through optogenetics m?id=method-of-the-year

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2025 SlidePlayer.com. Inc. All rights reserved.