DNA Repair. Spontaneous Alterations Depurination and Deammination.

Slides:



Advertisements
Similar presentations
Site-specific recombination
Advertisements

MB 207 – Molecular Cell Biology
MBV2010/BIO2140 Colloquium, March 6. RULES Multiple choice Only one correct answer seconds to answer No textbook, computer, mobile phone, please.
Homologous Recombination at the Molecular Level
Transposons & Mechanisms of Transposition
DNA Repair and Recombiantion. Methyl-directed mismatch repair (1) If any mismatch escapes the proof reading mechanisms it will cause distortion of the.
Replicação na presença de erros. Recombination at the Molecular Level Breakage and joining also directed by enzymes. Homologous recombination.
Microbial Genetics (Micr340)
25 February, 2005 Chapter 10 Gene Mutation: Origins and Repair Processes GAATTC  GTATTC A  a.
Transposons First discovered in plants. Transposition to a new site Transposons *Three classes of transposons Class I : Retrotransposons Class II: Transposons.
Chapter 5: DNA Replication, Repair, and Recombination
Transposition and transposable elements
Retroviruses and Retroposons
Genetic Recombination 3 by: Nouf alyami. Content I. INTRODUCTION. II. GENERAL RECOMBINATION III. SITE-SPECIFIC RECOMBINATION.
DNA Replication, Repair, and Recombination
DNA Recombination Mechanisms AHMP Objectives List the major classes of mobile genetic elements (we went over this before) Describe the process of.
DNA Recombination Roles Types Homologous recombination in E.coli
Gene and Chromosome. DNA is the genetic material.
Transposition Evidence Mechanisms: DNA-mediated RNA-mediated.
Recombination Homologous recombination Site-specific recombination Transposition Different sets of proteins are responsible for the different types of.
William S. Klug Michael R. Cummings Charlotte A. Spencer Concepts of Genetics Eighth Edition Chapter 15 Gene Mutation, DNA Repair, and Transposition Copyright.
Biological Roles for Recombination 1.Generating new gene/allele combinations (crossing over during meiosis) 2.Generating new genes (e.g., Immuno- globulin.
DNA Recombination.
Translesion DNA Synthesis Cells bypass lesions encountered at the replication fork during DNA synthesis and correct them after replication is finished.
Chapter 5 General Recombination.
Objectives of DNA recombination
Copyright © 2009 Pearson Education, Inc. Chapter 15 Lecture Concepts of Genetics Tenth Edition Gene Mutation, DNA Repair, and Transposition.
Genetic recombination: 1.Homologous Recombination 2. Site-Specific Recombination 3. DNA Transposition.
FQ. DNA Replication and Repair.
Chapter 11 Site-Specific Recombination & Transposition of DNA
Lecture 9 Site Specific Recombination and Transposition Quiz 5 due today at 4 PM.
Homologous Recombination
Introduction to Molecular Genetics Studiju materiāli / MolekularasBiologijas / Ievads MolGen / EN.
Copyright © 2009 Pearson Education, Inc. Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Chapter 22.
The Genetics of Bacteria and Their Viruses
Transposable Elements DNA Sequences That Change Positions in the Genome.
Final Journal Club Monday April 27 & Wed April 29 1.New techniques for genome editing & other purposes CRISPR TALEN Zn Finger Cre-Lox 2.New techniques.
GENETICS ESSENTIALS Concepts and Connections SECOND EDITION GENETICS ESSENTIALS Concepts and Connections SECOND EDITION Benjamin A. Pierce © 2013 W. H.
Repair of Damaged DNA DNA is the only cellular macromolecule that can be repaired DNA damage includes: base modifications nucleotide deletions or insertions.
1.Structures and Functions of Nucleic Acids 2.Organization and Content of Genomes 3.DNA Replication 4.The Mutability and Repair of DNA 5.DNA Recombination.
Bacterial Transposons Author Meenakshi Agarwal, Mehta Gunjan Mentor Dr. Santanu Ghosh.
Regulation of Bacterial Gene Expression Constitutive enzymes are expressed at a fixed rate. Other enzymes are expressed only as needed. –Repressible enzymes.
Genetics. Mutations of Genes Mutation – change in the nucleotide base sequence of a genome; rare Not all mutations change the phenotype Two classes of.
Recombination – read Chapter 11
Microbial Genetics Replication of chromosomal DNA Transcriptional control Mutation, repair, recombination Gene exchange in bacteria Genetic engineering.
Maintenance of genomes Copying the genome sequence (replication) Repairing damage to the genome sequence Rearranging genome sequences.
©2001 Timothy G. Standish John 15:4 4Abide in me, and I in you. As the branch cannot bear fruit of itself, except it abide in the vine; no more can ye,
BM102 Molecular Bioscience MUTAGENESIS AND REPAIR Dr Ellis.
MBV2010 Colloquium, March 10. RULES Multiple choice Only one correct answer seconds to answer No textbook, computer, mobile phone, please There.
Retroviruses and Trans(retro)posons
Homologous Recombination
Chapter 10 DNA Metabolism: Replication, Recombination, and Repair DNA polymerase & DNA Recombination.
Presentation Introduction of DNA Recombination Haoran Zhang Department of Chemical and Biological Engineering Tufts University.
Last Class DNA replication Chromosome replication DNA repair General Recombination.
Transposition and transposable elements
Microbial Genetics Eukaryotic microbes: fungi, yeasts Eukaryotic genome Chromosomal DNA Mitochondrial DNA Plasmids in yeast Prokaryotic.
Office Hours (midterm #1)
TRANSPOSABLE GENETIC ELEMENTS I
TRANSFERIMIENTO LATERAL DE GENES
Transposable Elements
Chapter 13: transposable elements
Transposons and Mechanisms of Transposition
Evolution of eukaryote genomes
Chapter 8, part C Microbial Genetics.
Chapter 14: Mutation & repair
Homologous Recombination
Transposable Elements
Homologous Recombination
Presentation transcript:

DNA Repair

Spontaneous Alterations

Depurination and Deammination

Thymine Dimer

Deamintation

Depurination

Double-Strand Break Repair

DNA Recombination

Junction

ssDNA Hybridization

Rec A in Homologous Recombinaton at DNA Synapsis

Holiday Junction

Resolving Holiday Junction

General Recombination in Mitotic and Meiotic Cells

Site Specific Recombination Moving of mobile genetic elements between non-homologous DNA Transpositional site-specific recombination –DNA only transposition Cut and Pase transposition Replicative transposition –Retroviral-like retrotransposition –Nonretroviral retrotransposition Conservative site-specific recombination

Bacterial Transposons

Cut-and-Paste Transposition

Replicative Transposon

Retrovirus

Site-specific recombintaion by a retro virus or a retrovirus-like retrotransposon

Nonretroviral Retrotransposon

Conservative site specific recombination

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2024 SlidePlayer.com. Inc. All rights reserved.