Division of Biostatistics Annual Report for 2004 and 2005 October 6, 2006

Mission Develop new statistical and bioinformatic methodologies, Collaborate with researchers outside of Biostatistics, Provide instruction in beginning and intermediate applied statistics and bioinformatics, Provide statistical consulting and grant preparation assistance services.

Basics Two subdivisions: Biostatistical Consulting Unit, Center for Bioinformatics and Molecular Biostatistics 12 faculty 7 staff 10 courses

Productivity - Research 29 methodological publications ( ) 134 collaborative publications ( ) 9 grants or contracts focusing on methodology active in grants as co-investigator or collaborator active in 2005 Peter Bacchetti elected Fellow of the American Statistical Association in 2004.

Productivity - Teaching Introductory courses (Biostat 183 and 187) enroll about 150 students per year. Our intermediate sequence, Biostat , taught primarily to the ATCR and MCR students, now enrolls 50 students. Vittinghoff, Glidden, Shiboski and McCulloch published a book for Biostat (Springer, 2005). New courses: BMI 209 – Statistical analysis of microarray data, Biostat 200 – Intro biostats for TICR and MCR students.

Productivity - Service Biostatistical Consulting Unit (Peter Bacchetti, Director) 332 brief consultations ( ) 284 paid projects ( ) Hired new Associate Director, Barbara Grimes, PhD Grant development assistance 130 grants ( )

Center for Bioinformatics and Molecular Biostatistics New course: BMI 209 – Statistical analysis of microarray data, New postdoctoral associate – Yuanyuan Xiao, PhD. More detailed report later in the year, from Mark Segal, Director.

Future Plans Revitalized seminar series – Mitch Gail will be visiting in the Spring, Co-sponsor a small workshop on adaptive trial design, Revamp both services and teaching curriculum as CTSI develops.