Biochemistry
Matter Anything that has mass and takes up space
Atoms basic building blocks of matter that make up everyday objects –90 naturally occurring kinds of atoms –Scientists have been able to make about 25 more
Element Made of only 1 type of atom
Elements to Know Carbon (C) Hydrogen (H) Oxygen (O) Nitrogen (N) Phosphorous (P)
Compounds 2 or more types of atoms combined in a fixed ratio H 2 O: Water CO 2 : Carbon Dioxide
Water Polar molecule: molecule with regions of + and – charges Cohesion: attraction between molecules of the same substance Adhesion: attraction between molecules of 2 different substances –Capillary action Solid ice is less dense than liquid water
Organic vs. Inorganic Compounds Organic Compounds: contain carbon –Almost always contains hydrogen –Usually contain oxygen and nitrogen Inorganic Compounds: do not contain carbon –Exceptions Carbon dioxide Calcium carbonate
Macromolecules Large molecules formed by joining smaller molecules together Biological Macromolecules are arranged in 4 categories –(1) Carbohydrates –(2) Lipids –(3) Proteins –(4) Nucleic Acids
Polymers Molecules made from repeating units of monomers (small molecule) Monomer Polymer
Monomers Polymers
1. Carbohydrates Store energy and provide structural support Contain carbon, hydrogen, and oxygen Formula (CH 2 O) n –n indicates # of units in the chain
Carbohydrates Sugars (end in –ose) –Monosaccharides: 1 sugar –Disaccharides: 2 sugars –Polysaccharides: many sugars
Storage of Sugars organisms store excess sugar in polysaccharides –Starch: plants –Glycogen: animal
Structure Cellulose: cell wall in plants Chitin: shells of insects
How are disaccharides and polysaccharides made from monosaccharides? Dehydration Synthesis: Putting together Removing water
How are polysaccharides and disaccharides broken back down into monosaccharides? Hydrolysis: add water to break bond
2. Lipids Fats, oils, waxes Contain carbon, hydrogen, and oxygen Part of cell structures and serve as back up energy supply
Fat structure Glycerol + 3 fatty acids (combined by dehydration synthesis) hydrophillic hydrophobic
Saturated vs. Unsaturated Fats Saturated: all single Carbon to Carbon bonds (straight chain) Unsaturated: one or more double bonds (bent chain) oils butter
3. Proteins Contain carbon, hydrogen, oxygen, and nitrogen –Can contain sulfur and phosphorous Cell communication, enzymes, structure, antibodies
Amino Acid Carboxyl group Amino group
20 Amino Acids
Protein Structure Amino acids bonded together by dehydration synthesis
Peptide Bond Bond which forms between amino group of one amino acid and carboxyl group of another amino acid
Dipeptide: 2 amino acids bonded together Polypeptide: long chain of amino acids
4. Nucleic Acids Contain carbon, hydrogen, oxygen, phosphorous, and nitrogen Include DNA and RNA Hereditary material protein synthesis
DNA Deoxyribonucleic acid Long chain of repeating nucleotides –5 carbon sugar (deoxyribose), phosphate group, nitrogen base Double helix 2 strands
RNA Ribonucleic acid 5 carbon sugar (ribose), phosphate group, nitrogen base One Strand
Deoxyribose vs. Ribose
Macromolecule (Polymer) Building Block (Monomer) CarbohydrateMonosaccharides (sugars) LipidsFatty Acids ProteinsAmino Acids Nucleic AcidNucleotides