Chem 3550 Chapter 16: Production of NADH and NADPH: The Citric Acid Cycle, the Glyoxylate Cycle (Skip), and the Pentose Phosphate Pathway

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These are all very important! Know names and cofactors, as well as reactants and products.

Rearrange to facilitate later oxidation (cannot oxidize 3 ° carbon) 4 Carbons 6 Carbons Loss of CO 2 Oxidation of alcohol to ketone (note use of NAD + ) 5 Carbons Similar to PDC reactions for Acetyl- CoA formation High Energy Compound GTP (or ATP) production Oxidation of alkane to alkene (note use of FAD); Succ. Deh. Is a membrane- bound enzyme Hydration Reaction is stereospecific Oxidation of alcohol to ketone (note use of NAD + ) 4 Carbons

This is something you should be very comfortable with

Know this! Regulation is very important!

Summary

Also known as E 1 Second level of control of PDC in eukaryotes Kinase: enzyme to puts on a phosphate Phosphatase: enzyme that takes of a phosphate

Amphibolic nature of CAC X

Pentose Phosphate Pathway NADPH produced! Used for lipid biosynthesis