TREATMENT PLANNING PHOTONS & ELECTRONS Karen P. Doppke 3/20/2007
Regions of Radiation Field Considered in Dose Calculations
DOSE TO A POINT IN TISSUE Major Processes that Effect Dose in Tissue from Photon Beams Inverse Square Law Photon Attenuation Photon Scatter
Dose Calculation Methods Used to Determine Dose at a Point in a Patient Correction Based Methods % Depth Dose Calculations Tissue Maximum/Phantom Ratios Tissue-Air Ratios Model Based Methods Pencil Beam Methods Convolution Superposition Monte Carlo Calculations
The General Form of Equation Used to Calculate Dose at Depth in the Patient TPR (d, r, h ) = Dose at Depth / Dose at Reference/Max
10 Mv X-ray Beam
Isodose Curves High Energy
Variation in Dose for Various Energy Beams
COMPARE MONTE CARLO DOSES IN LUNG
Comparison Dose Distribution 6 MV X-Rays
Conformal Planning Process PATIENT DATA SET/S CT, MRI, PET DEFINATION OF TARGET AND NORMAL TISSUES PRESCRIPTION DOSE and FRACTIONATION TOTAL DOSE TO VOLUMES DOSE TO NORMAL TISSUES
EXAMPLE OF A CONFORMAL PLAN The prescription should include the total dose to the target volumes, the fractionation, a statement of the expansion of the GTV to the CTV and PTV. The dose limits to the normal tissues that are near the site of treatment need to be defined.
ICRU 62
EXAMPLE OF TREATMENT VOLUMES
TREATMENT VOLUMES GTVCTVITVPTV
NORMAN TISSUES NEAR TREATMENT SITE SPINAL CORD< ~45 Gy LIVER <~25Gy/100%, 30Gy/35%, 35Gy/25% KIDNEYS<~23Gy/66% LUNG<~30Gy/40%, 60Gy/20% HEART<~30Gy/100% LV, 45Gy/100% (atrium)
AP/PA OPPOSED FIELDS
DVH FOR TISSUES AP/PA CTV PTV Liver Lung RT Kidney RT Heart
FOUR FIELD PLAN AP/PA/RLAT/LLAT
DVH 4 FIELD PLAN CTV PTV Liver Heart Kidney RT Lung RT
5 FIELD PLANE AP/RA/RP/LP/LA
DVH 5 FIELD PLAN CTV PTV Liver Lung RT Heart Kidney RT
CTV Lung RT Kidney RT
Stereotactic Radiosurgery 1905: Introduction of stereotactic equipment 1908: Mapping of brain in 3 planes 1918: First stereotactic frame for humans in London 1940: Greatest strides in intracranial applications began
Stereotactic Radiosurgery 1982: Modified Linear Accelerator
Stereotactic Radiosurgery SRS Frame Placement
STEROTACTIC RADIATION THERAPY SRT
Fractionated Stereotactic Radiation Therapy Fractionated Stereotactic Radiation Therapy(SRT) combines the target and dose localization characteristics of SRS with the biologic advantages of dose fractionization
STEROTACTIC RADIATION SURGERY SRS
Fractionated Stereotactic Radiation Therapy