Software and Global Health: Assessing Vaccine Cold Chains from National Equipment Inventories Richard Anderson Department of Computer Science and Engineering.

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Presentation transcript:

Software and Global Health: Assessing Vaccine Cold Chains from National Equipment Inventories Richard Anderson Department of Computer Science and Engineering University of Washington 1/5/2012 Change Seminar 1

What this talk is about The development and deployment of software for evaluating the vaccine cold chains in developing countries Software has been used in four African countries to analyze recently completed cold chain inventories Bigger issues Use of information in supporting health systems Introduction and sustainability of technology 1/5/2012 Change Seminar 2

Three themes 1.Implications of inventory based cold chain planning to global health 2.Stakeholders for global health software 3.Software technologies for national health systems 1/5/2012 Change Seminar 3

Cold Chain Equipment Manager (CCEM) software CCEM Project at PATH Develop software to support inventory based cold chain analysis and planning Project initiated in 2006 with UNICEF and WHO Application builds on public health expertise and global cold chain standards CCEM Software Current version is a Microsoft Access application Modest sized database with custom analysis and reporting Inventory based cold chain planning Understand capacity of the cold chain with respect to vaccine requirements Optimize allocation of equipment to minimize costs 1/5/2012 Change Seminar 4

Cold Chain Structure 1/5/2012 Change Seminar 5 National Vaccine Store Regional Store District Store Regional Store District Store Vaccine Manufacturers Health Center Health Post

1/5/2012 Change Seminar 6 Cold Chain

1/5/2012 Change Seminar 7

Cold chain inventory What is the status of a country’s cold chain? How many refrigerators? What types are they? How old? Are they working? Are they big enough for the required vaccines? Where are they? 1/5/2012 Change Seminar 8 Country A: 5306 facilities, 4946 refrigerators Country B: 827 facilities, 1426 refrigerators Country C: 2846 facilities, 3153 refrigerators Country D: 1605 facilities, 3080 refrigerators

Inventory Based Cold Chain Capacity Analysis 1/5/2012 Change Seminar 9 Cold Chain Planning Tool (CCEM) Capacity analysis Reports Equipment requirement list Health facility list Demographic data Refrigerator inventory Vaccine schedule

Cold Chain Equipment Manager (CCEM) Software 1/5/2012 Change Seminar 10 1/5/2012Change Seminar 10

CCEM History 2006 CCEM development starts at the TechNet Consultation in Mexico 2007 CCEM piloted in collaboration with Uganda EPI team, WHO/IST, and UNICEF/TACRO CCEM migrated to MS Access 2007, with a new user interface and stability enhancements 2010 Release of CCEM at TechNet Consultation in Kuala Lumpur 2011 CCEM Inventories and analysis in four African countries 1/5/2012 Change Seminar 11

CCEM Reports: Facilities 1/5/2012 Change Seminar 12

Infrastructure (Electricity) 1/5/2012 Change Seminar 13

Country Equipment Profiles 1/5/2012 Change Seminar 14

Country reports CCEM analysis used to support country cold chain reports Reports prepared by country EPI teams Circulated to WHO, GAVI and donors 1/5/2012 Change Seminar 15

Results from the four countries (Summary) 1/5/2012 Change Seminar 16 Country ACountry BCountry CCountry D Overall cold chain readiness Capacity by level: Stores (national/regional) District stores Health centers (public/private) Peripheral facilities Equipment Quality/Age Shortages with PCV 13 Shortages with Rotavirus Risk area identifiedCapacity at district and national store for Rota launch Cold room capacity at regional stores Cold room capacity at national stores for Rota launch Large percentage of equipment >10 years old

Estimated costs to address cold chain equipment deficiencies in four countries 1 (USD in 000’s) 1/5/2012 Change Seminar 17 Base Schedule with PneumoBase Schedule with Pneumo and Rota CountryILR units Gas/Ker units Cold rooms Cost USD in 000’s ILR units Gas/Ker units Cold rooms Cost USD in 000’s Country A ,825 Country B Country C , ,481 Country D Notes 1. Equipment assignment to meet all shortages at government health facilities and storage sites. A medium sized presentation of Rotavirus vaccine was assumed. Equipment assignments following country preferences. Inventory data from some countries was preliminary. There is a high variability in costs for cold rooms due to construction and setting up the site. 2. Country A’s analysis assumes three month supply intervals to district vaccine stores 3. Country B has some cold rooms on order or waiting installation. A quantity of new refrigeration equipment is available for allocation and not reflected in this analysis. 4. Country C has 11 regional vaccines stores in the planning phase. The inventory did not account for new equipment on hand awaiting allocation. 5. Country D’s analysis does not consider replacement of out of date equipment. The cost per annual birth of required equipment for introduction of Pneumo and Rota (Total cost / annual births) is $1.32 for Country A, $0.87 for Country B, $2.11 for Country C, and $1.40 for Country D.

Vaccines and Immunization One of the worlds most effective health interventions Wide coverage of basic vaccines Diphtheria, Pertussis, Tetanus: 77% in poorest countries Tremendous reduction in deaths Some diseases close to elimination Large scale global programs Decade of Vaccines Introduction of new vaccines Pneumococcal and Rotavirus vaccines 1/5/2012 Change Seminar 18 Polio 1990 Polio 2008

Who are the stakeholders? 1/5/2012 Change Seminar 19 Donors Global Organizations Non- governmental Organizations Ministry of Health Health System Cold Chain Logisticians Expanded Program of Immunization Private Sector

New Vaccine Introduction Timeline 1/5/2012 Change Seminar 20 IVAC VIMS report, March 2010

Old vs. New Vaccines 1/5/2012 Change Seminar 21 4,100 doses Polio and Measles $ doses Rotavirus $4687

Is Chad ready to introduce the Rotavirus vaccine? Is the cold chain of adequate capacity and quality to safely store vaccines from entry in to the country to use at peripheral health facilities? What areas of the cold chain should be targeted for improvement? How much will it cost? 1/5/2012 Change Seminar 22

GAVI Alliance Global Alliance for Vaccines and Immunisation Founded in 2000 to develop long term funding mechanism for vaccines in developing countries Building country commitment Financing Market based solutions Reduced cost vaccines for developing countries Funding mechanism Eligible countries request funding for vaccines USD 7 Billion funding, countries have been funded 1/5/2012 Change Seminar 23

WHO and UNICEF Global organizations with international, global, and country presence Set global standards and policies Substantial influence on country policies UNICEF Scale-up in Immunization Vaccine Logistics Temperature Monitoring Country Cold Chain Inventories Global network of consultants 1/5/2012 Change Seminar 24

Country EPI Expanded Program of Immunisation Department in ministry of health Responsible for all of immunization and vaccination Focus on immunization coverage Often dealing with emergencies Cold chain logistics Department inside of EPI managing the cold chain and vaccine shipments Responsible for vaccines from national store to facilities Manage equipment in government facilities 1/5/2012 Change Seminar 25

Value proposition for inventory based cold chain planning Global level “I want to know if a country’s cold chain is ready for introduction of a new vaccine” Donors “What resources are needed to strengthen the country’s cold chain” EPI “I need to manage the country’s vaccination programs and respond to external requirements” Logistician “I need to manage the cold chain equipment in the system” 1/5/2012 Change Seminar 26

Results from CCEM data sets Successful in completing inventories and generating information for national cold chain plan Simple analysis methodology identifies bottlenecks in the cold chain Quantifies costs for upgrades Analysis of energy costs Substantial differences between countries Country readiness analysis Assess cold chain capacity with respect to vaccine introduction High level analysis focusing on structure of cold chain Exploration of scenarios What are the energy cost savings in replace gas equipment by electric equipment in facilities with access to electricity? What is the impact on cold chain capacity requirements of reducing country vaccine delivery periods from three months to one month? 1/5/2012 Change Seminar 27

Sustainability and Adoption What are the prospects for sustained and expanded use of CCEM at the country level? What did we learn from the four countries? 1/5/2012 Change Seminar 28

Facility and Equipment Inventory Dominant cost for use of CCEM is inventory cost Estimated inventory costs $50K - $200K Controversy around CCEM relates to cost and feasibility of an inventory Conducting a cold chain inventory: Start with a list of all health facilities in the country Determine information to be collected Train enumeration teams Rent lots of land rovers Visit all facilities and conduct inventory Enter data into database Review and clean the data 1/5/2012 Change Seminar 29

Adoption of CCEM by countries Country A Inventory and country plan in process, decided to use CCEM to support inventory and planning. Country B NGO supporting EPI strengthening brought in PATH to support inventory and planning work. Country C Already using older version of CCEM for cold chain inventory. Refreshed inventory to work with new version of software. Country D WHO supported inventory and country plan, with CCEM brought in to structure inventory. 1/5/2012 Change Seminar 30

Model for sustainable use Facility and equipment inventory kept up to date by country Inventory must provide value to logistics system Mechanism for updating the inventory from district level Use of inventory data in cold chain planning and reporting Global support for inventory based planning Standardization of inventory and indicators Alignment with other tools Resources for maintenance and development of software Possibly a consultant model for planning 1/5/2012 Change Seminar 31

Summary of country introduction CCEM adopted as an inventory solution Structure for inventory Database with data entry Reporting Developers viewed CCEM as a planning tool (that required having a database) Tension during introduction workshops between the planning and inventory components Results from working with inventories have validated the planning component Usability of the application was a barrier to adoption New model for application: Country use for inventory and asset management Consultant support for planning 1/5/2012 Change Seminar 32

Base technologies CCEM implemented as MS Access 2007 application Development History CCEM 1.0 – PATH with contract developer CCEM 2.0 – External software developer CCEM 2.1 – PATH with project management and contract developer CCEM 3.0 – ???? Competition with MS Excel Tools MOH Environment strictly Windows / Office environment Mix of Windows XP / Windows 7 Internet access at MOH Reasonable to plan for Internet access to District level (likely with cellular modem) 1/5/2012 Change Seminar 33

Future Application Architecture 1/5/2012 Change Seminar 34 Cold chain inventory Reports Web based planning module Database Management Remote data entry

DHIS 2 Health Information Systems Programme (HISP) Founded by University of Oslo in 1994 HISP India established in 2000 Software for collection of health indicators Focus on use of data District Health Information System (DHIS) Initial version of software in MS Excel Current software (DHIS2), web based system with Java back end Deployment in roughly 20 countries in Africa Deployment in roughly 20 states in India Basic software provides data entry and aggregation Potential platform for new cold chain inventory tool Extensions needed to handle fixed assets 1/5/2012 Change Seminar 35

Sustainability of Asset Inventories Develop technology and methodology for creation and update of asset inventories Technology Tools for collection and update of inventory information Work process System where there are benefits to keeping the information up to date Value from the inventory Business process for management Value from reporting data 1/5/2012 Change Seminar 36

Health center data Key: Electric refrigeration Gas/Kerosene refrigeration No refrigeration Poor fuel availability Gas/Kerosene available > 8 hours of electricity Information Visualization 1/5/2012 Page 37 Inventory data plotted with facility GPS data Change Seminar

(Simple) Health System Modeling CCEM relies on very simple models Storage requirement = doses X volume per dose The challenge for application like CCEM is to make the modeling easy to use. Simulation based games solve the same interface problems that come up in CCEM. Assignment of assets to locations on a map Setting conditions over regions Ease of use / learnability essential 1/5/2012 Change Seminar 38

Questions or Comments? 1/5/2012 Change Seminar 39 Richard Anderson, cs.washington.edu/homes/anderson change.washington.edu Software Downloads: